Author

Todd Fitzpatrick

With a doctorate in biochemistry, Todd Fitzpatrick has worked for 20 years in analytical chemistry and structural biology. He directs mass spectrometry services at a proteomics core facility, analyzing therapeutic antibodies and engineered proteins. His research support involves mapping post-translational modifications, profiling intact glycans, and assessing higher-order protein structures for academic and industrial investigative groups. Fitzpatrick earlier operated high-resolution mass spectrometers in a university analytical facility, building expertise in liquid chromatography and biophysical characterization after graduating with a bachelor of science in chemistry.

What is the AlphaLISA Assay and How Does It Work?Tests
Histidine Protonated States in Protein Architecture and Function Chemistry
Protein Expression and Purification Protocol: Practical Steps Biology
What Is Differential Scanning Fluorimetry?Chemistry
Chemoproteomics: Research Strategies and New Perspectives Chemistry
What Is Activity Based Protein Profiling?Biology
CETSA Overview: Protein Denaturation and Drug Target Validation Biology
trRosetta for Accurate Protein Structure Modeling Biology
The Alfa Tag Nanobody System for Protein Research Biology
Fast PETase: Reaction Mechanisms and Engineering Tactics Chemistry
What Is CE-SDS? Capillary Electrophoresis for Proteins Chemistry
What Is Glycan Analysis and How Does It Work?Tests
Why Is Imidazole Used in Protein Purification?Chemistry
Predicting Protein Structure With Evolutionary Language Models Biology
Cell-Free Protein Expression: Current Approaches & Applications Biology
ModelAngelo: Automating Atomic Model Building in Cryo-EM Biology
What Is Peptide Mapping and Why Is It Important?Tests
The P-Loop Loop: Structure, Function, and Importance Biology
What Is Rosetta Protein Modeling and How Is It Applied?Biology
What Is Enzyme Library Design and How Does It Work?Biology
Superdex 200 Increase 10/300 GL: Principles & Practical Use Chemistry
Glycosylation Site Prediction: A Look at Its Importance Genetics
Biolayer Interferometry: Principles and Applications Chemistry
The VHH Structure and Its Unique Functional Advantages Biology
scFv Purification: An Overview of Critical Methods Biology
Biolayer Interferometry vs. SPR: Which Is Better?Chemistry
What is Carbamidomethyl’s Role in Protein Science?Chemistry
A General Nanodisc Protocol: Assembly and Key Uses Chemistry
mirFP670nano: The Smallest Near-Infrared Fluorescent Protein Biology
The PROTAC Structure and How It Triggers Degradation Chemistry