What to Expect With a Transesophageal Echocardiogram

A transesophageal echocardiogram (TEE) is an ultrasound of your heart taken from inside your esophagus, the tube connecting your throat to your stomach. Because the esophagus sits right behind the heart, the probe can capture much sharper images than a standard echocardiogram performed from the outside of your chest. The procedure typically lasts 20 to 40 minutes, involves sedation and a numbing spray for your throat, and most people go home the same day. It sounds more intimidating than it usually turns out to be, but knowing each step in advance genuinely helps.

Why Your Doctor Ordered a TEE

A standard transthoracic echocardiogram (TTE), the kind where a technician presses a wand against your chest, works well for many heart conditions. But ribs, lungs, and body tissue sit between the probe and the heart, which can blur the picture. A TEE bypasses all of that. The probe sits just millimeters from the back wall of the heart, so structures that are hard to see from the chest surface become much clearer.

There are several common reasons a TEE gets ordered rather than a regular echo:

  • Blood clots in the heart: TEE is considered the gold standard for finding or ruling out clots in the left atrial appendage, a small pouch where clots tend to form in people with atrial fibrillation. Your doctor may need to confirm no clot is present before a procedure like cardioversion.
  • Valve infections: When infective endocarditis is suspected, TEE is significantly more sensitive than a chest-surface echo at detecting vegetations on the valves. In one study, TEE identified valve growths in about 87 percent of confirmed cases compared with 60 percent for TTE, and it was especially better at catching smaller growths under one centimeter.
  • Valve disease before surgery: Three-dimensional TEE can show the geometry and movement of a leaking or damaged mitral valve in real time and from multiple angles, giving surgeons critical information for planning a repair.
  • Hole in the heart: A patent foramen ovale (PFO) is a small flap-like opening between the upper chambers of the heart. TEE with a bubble study, where agitated saline is injected into a vein, is a primary way to diagnose it. If bubbles cross from the right side of the heart to the left within a few heartbeats during a bearing-down maneuver, a PFO is present.
  • Aortic problems: TEE can identify atherosclerosis, dissections, and other issues in the thoracic aorta, and it helps detect complications after aortic surgery.

TEE is also used in real time during heart surgery and catheter-based procedures. It guides the team during steps like crossing the wall between the upper chambers, closing the left atrial appendage, and repairing or replacing valves without open-heart surgery.

How to Prepare

You will be told not to eat or drink for several hours before the test, usually at least four to six hours. The goal is to reduce the chance of vomiting and inhaling stomach contents into your lungs while sedated. Interestingly, research has questioned whether strict fasting actually guarantees an empty stomach or meaningfully reduces aspiration risk, but fasting before sedation remains standard practice, and you should follow your care team’s instructions.

Your doctor or nurse will also ask about your medical history before the procedure. They want to know about any swallowing problems, previous esophageal surgery, known narrowing of the esophagus, a history of radiation to the chest or neck, or conditions like esophageal varices (enlarged veins in the esophagus often related to liver disease). Upper gastrointestinal injuries are the most commonly described complications of TEE, so identifying people with anatomical abnormalities or fragile tissue ahead of time is a key safety step. In some cases, the team may decide the risks outweigh the benefits and choose an alternative imaging method instead.

Let your team know about any medications you take, especially blood thinners. You generally do not need to stop most medications, but your doctor will give you specific guidance. Also mention any allergies, particularly to numbing agents like lidocaine or benzocaine, and any history of reactions to sedation.

What Happens During the Procedure

You will change into a hospital gown and lie on your left side on an exam table. An IV line will be placed in your arm, and you will be connected to monitors tracking your heart rhythm, blood pressure, and oxygen levels throughout the test.

Before the probe goes in, the back of your throat will be numbed. This is usually done with a spray or gargle containing a local anesthetic like lidocaine or benzocaine. The numbing helps suppress the gag reflex and makes the insertion more comfortable. A rare but real side effect of these throat-numbing agents is a condition called methemoglobinemia, where the blood temporarily loses some of its ability to carry oxygen. The risk goes up when lidocaine and benzocaine are used together, which is why many centers stick to one or the other.

Next comes sedation through your IV. The most common approach is moderate or “conscious” sedation, often using a drug like midazolam (a short-acting sedative) sometimes combined with a pain reliever. You will feel drowsy and relaxed, and many people have little memory of the procedure afterward. You are not put under general anesthesia for a standard diagnostic TEE, though general anesthesia is used when TEE is performed during cardiac surgery.

Once you are sedated and your throat is numb, you will be asked to swallow as the doctor gently guides the probe, a thin flexible tube with a small ultrasound transducer at the tip, past your tongue and into your esophagus. This is the part most people dread, and it is the most uncomfortable moment, but it passes quickly. A mouth guard will be placed between your teeth to protect both you and the probe. Once the probe is positioned behind the heart, you will not feel much. You can still breathe normally because the probe goes into your food pipe, not your airway.

The cardiologist then adjusts the probe’s angle and depth to capture views of different heart structures. A standard comprehensive exam involves imaging from several positions within the esophagus, including the mid-esophageal level (where views of all four chambers, the valves, and the aorta are obtained) and the transgastric level (where the probe sits in the upper stomach to image the ventricles from below). Modern probes can rotate the imaging plane electronically, so the doctor does not need to physically twist the probe much. The whole imaging portion usually takes 10 to 30 minutes depending on what needs to be evaluated.

If a bubble study is part of the test, a nurse will inject agitated saline through your IV at a specific moment, and you may be asked to bear down as if straining. This helps the doctor check for openings between the heart chambers.

What It Feels Like

The honest answer is that it is uncomfortable but manageable for most people, and the sedation does a lot of the heavy lifting. The worst part is typically the initial swallowing of the probe. You may feel a gagging sensation, pressure in your throat, and a strong urge to swallow. Once the probe is in place, the discomfort usually fades to a background awareness of something being in your throat. Some people feel mild pressure or an urge to belch during the exam. Because of the sedation, many patients recall very little of the actual procedure.

Anxiety before a TEE is common and completely normal. Research has shown that a brief psychological preparation session before the procedure, where a clinician explains each step and teaches simple coping strategies, can meaningfully reduce both anxiety and discomfort during the exam. In one study, patients who received this kind of preparation were three times less likely to need a sedative, and those who did received a much lower dose (an average of 0.5 mg of midazolam versus 2.4 mg in the group without preparation). Physicians also reported greater ease performing the procedure on prepared patients. If your hospital offers any kind of pre-procedure education or coaching, take advantage of it.

Risks and Complications

TEE is considered a safe procedure overall, but it is not risk-free. The most important thing to know is that serious complications are rare.

The most common issue after the procedure is a sore throat, which typically resolves within a day or two. Some people experience minor nausea or a hoarse voice. These are nuisances, not medical emergencies.

Serious complications involve injury to the esophagus or, less commonly, the stomach. Upper gastrointestinal injuries are the most frequently described serious problems, but they remain uncommon. The most feared complication is esophageal perforation, a tear through the wall of the esophagus. Large case series report this happening in fewer than 0.1 percent of procedures. When it does occur, it is dangerous because it can lead to infection spreading into the chest cavity, and mortality from esophageal perforation has been reported at close to 30 percent. The rarity of this event is worth emphasizing: it is an extremely uncommon outcome, but it is the reason the screening questions about esophageal disease matter.

For people with esophageal varices related to liver cirrhosis, there has historically been concern about causing bleeding. A meta-analysis found that the overall rate of bleeding complications in patients with cirrhosis undergoing TEE was about 0.37 percent. However, the rate was higher, roughly 1 percent, when TEE was performed during liver transplant surgery, compared with essentially zero when performed for other reasons outside the operating room. So the context and the patient’s overall condition matter significantly.

Side effects from sedation, such as a drop in blood pressure or breathing that slows too much, are managed in real time by the monitoring team. Allergic reactions to the throat-numbing agent or sedation drugs are possible but uncommon.

After the Procedure

Once the probe is removed, you will rest in a recovery area while the sedation wears off. This usually takes 30 minutes to an hour. Your throat will remain numb for a while, so you will not be allowed to eat or drink until the numbness fades, usually one to two hours after the test. Eating or drinking before you can swallow safely risks choking or aspiration.

Because of the sedation, you should not drive, operate machinery, or make important decisions for the rest of the day. You will need someone to take you home. Most people feel back to normal by the next morning, though a mild sore throat may linger for a day.

Your cardiologist may share preliminary findings with you before you leave, or the full results may take a day or two if detailed analysis is needed. If the TEE was done to look for a clot before cardioversion, or to guide a decision about surgery, your doctor will typically discuss the findings and next steps promptly.

When TEE Is Used During Surgery or Catheter Procedures

If you are having a TEE as part of a cardiac surgery or a catheter-based intervention, your experience will be different from a standalone diagnostic TEE. You will be under general anesthesia, so you will not be awake for the probe insertion and will have no awareness of the imaging happening during the case.

Intraoperative TEE has become essential for many heart procedures. During transcatheter valve repairs, for example, echocardiographic guidance helps the interventional team navigate catheters, cross the wall between the upper chambers of the heart, position devices correctly, and immediately check the result. It is also used during left atrial appendage closure, PFO and atrial septal defect closure, and repair of leaks around prosthetic valves. The real-time feedback means the team can catch and address problems before the procedure ends, rather than discovering them on a follow-up study days later.

Alternatives If You Cannot Have a TEE

Some people cannot undergo TEE safely. If you have a known esophageal stricture, a recent esophageal surgery, an active esophageal bleed, or certain other conditions affecting the upper digestive tract, your doctor will look for another way to get the images they need.

Cardiac MRI is one alternative. It offers excellent image resolution without any probe insertion and is noninvasive, making it an attractive option for people unable or unwilling to undergo TEE. However, cardiac MRI takes longer, is not available everywhere, and is not practical for real-time procedural guidance.

Intracardiac echocardiography (ICE) is another option, particularly during catheter-based procedures. Instead of going through the esophagus, the ultrasound probe is advanced through a vein and placed directly inside the heart. A study comparing ICE and TEE for combined atrial fibrillation ablation and left atrial appendage closure found that ICE was associated with shorter procedure times, less fluoroscopy exposure, and fewer post-procedure side effects like esophageal discomfort, nausea, and low blood pressure. ICE also avoids the need for general anesthesia, which TEE-guided interventional procedures often require. The trade-off is that ICE adds the cost of a disposable catheter and requires a skilled operator comfortable working with the intracardiac views.

CT angiography of the heart is sometimes used as well, particularly for evaluating the aorta or planning structural interventions. It involves radiation exposure and contrast dye, which are their own set of considerations, but it provides excellent three-dimensional anatomical detail.

TEE in Infants and Children

TEE is not just an adult procedure. Children with congenital heart disease often need detailed imaging during surgery, and standard adult-sized probes are too large for a small child’s esophagus. Miniaturized probes, sometimes called micro-TEE probes, have been developed specifically for this population.

Studies evaluating these tiny probes in neonates and infants, including babies weighing as little as 2.5 kilograms, have found that they produce high-quality images without causing problems with breathing or blood flow. One study of 33 infants aged 3 days to 2 years reported good-quality images in all patients with no complications from probe insertion or use. Separate evaluations in pediatric cardiology settings have confirmed the micro-TEE to be both safe and effective in neonates and young children, expanding the role of TEE in managing complex congenital heart repairs that are increasingly performed at very young ages.

What Three-Dimensional TEE Adds

If your report mentions 3D or real-time 3D TEE, this refers to newer probe technology that captures depth in addition to the usual flat image. The difference matters most for valve disease. A standard two-dimensional TEE shows a cross-section of a valve at any given moment, but a 3D TEE can display the entire valve face as if the surgeon were looking down at it during an open-heart operation. This “surgeon’s eye view” lets the team see exactly which part of the valve is prolapsing or leaking, and it can visualize the valve in motion from different perspectives, something even direct surgical inspection cannot do because the heart is stopped during open-heart surgery.

Three-dimensional TEE has become particularly valuable for planning and guiding mitral valve repair. By mapping the precise location and extent of damage before and during the procedure, it helps surgeons decide on the best repair strategy and immediately verify that the repair worked. For catheter-based interventions like transcatheter mitral valve repair, 3D guidance has moved from a nice addition to a near-essential tool at many centers. If you are having a TEE specifically to evaluate a valve problem before planned surgery, there is a good chance the exam will include 3D imaging as part of the standard protocol.

Kristina Cook

With a bachelor of science in nursing, Kristina Cook, RN, CCRN, works as a float nurse in a hospital outpatient testing department. She rotates between the stress lab, vascular studies, and the EMG suite, assisting with cardiac, circulatory, and neuromuscular assessments. Cook guides patients through procedure prep and monitors them during diagnostic testing.