Why Does My Upper Lip Sweat When I’m Sick?

Many people notice their upper lip or face becomes noticeably sweaty when they are feeling unwell, especially during an illness. This experience, while sometimes uncomfortable, is a normal physiological response. It indicates the body’s systems are managing internal conditions during stress, such as fighting infection. This localized sweating is part of the broader mechanism the body employs to maintain its temperature balance.

How the Body Regulates Temperature

The human body maintains a stable internal temperature, around 98.6°F (37°C), through thermoregulation. The hypothalamus, a small region in the brain, acts as the body’s thermostat, constantly monitoring blood temperature and coordinating responses to keep it within a narrow range.

When the body’s internal temperature rises, the hypothalamus sends signals to activate cooling mechanisms. One primary method involves sweat production from eccrine sweat glands, distributed across most of the body’s surface. These glands release a watery fluid onto the skin, and as this sweat evaporates, it draws heat away from the body, cooling it down.

Sweating During Illness

During an illness, particularly when a fever develops, the body’s temperature regulation system undergoes a temporary adjustment. The immune system, in its effort to combat infection, releases substances called pyrogens. These pyrogens travel to the hypothalamus and effectively “reset” the body’s temperature set point to a higher level.

This elevated set point prompts the body to increase heat production and reduce heat loss, leading to the onset of a fever. Once the infection begins to subside or fever-reducing medications are taken, the hypothalamic set point returns to normal. The body then initiates a cooling phase, often marked by increased sweating and vasodilation, to bring the core temperature back down. This process is sometimes referred to as “sweating out a fever.”

Why Facial Sweating Occurs

The noticeable sweating on the face, including the upper lip, during illness is largely due to the high concentration of eccrine sweat glands in this region. The face, scalp, and neck are among the areas with the highest density of these glands, which are primarily responsible for thermoregulatory sweating. This abundance means that when the body initiates sweating to cool down, these areas will produce a significant amount of perspiration.

Sweat gland activity is controlled by the autonomic nervous system, specifically the sympathetic nervous system. The sympathetic neurons that innervate sweat glands release acetylcholine to stimulate sweat production. This neural pathway ensures that sweat glands respond efficiently to signals from the hypothalamus.

During illness, the body’s widespread thermoregulatory efforts activate these highly innervated facial sweat glands, making the sweating particularly apparent. Individual differences in sweat gland distribution and the sensitivity of the sympathetic nervous system can also contribute to variations in how much and where people sweat when they are sick. Sweating on the face, chest, and back is triggered by heat stimuli, distinguishing it from emotional sweating that often affects the palms and soles.

When to Consult a Doctor

While upper lip sweating during illness is a normal response, there are situations where it warrants medical attention. If excessive sweating is accompanied by severe symptoms like confusion, difficulty breathing, chest pain, or lightheadedness, immediate medical help should be sought. These symptoms could indicate a more serious underlying condition.

Consult a doctor if the sweating is unusually persistent, causes significant distress, or does not have an an obvious cause. If a high fever lasts for an extended period or does not respond to fever-reducing medication, medical advice is recommended. Any sudden increase in sweating or unexplained night sweats also warrants a discussion with a healthcare provider.