Why Does My Hand Hurt When Shaking Hands?

The hand is composed of 27 bones, numerous ligaments, and a complex network of tendons. When a simple social exchange like a handshake causes sudden, sharp, or throbbing pain, it can be confusing. This gesture applies a distinct combination of pressure, grip, and slight rotation that can expose underlying vulnerabilities in the wrist and hand structure. This article explores the specific medical conditions aggravated by this movement and outlines the steps necessary for immediate relief and long-term recovery.

Common Conditions Triggered by Handshakes

One of the most frequent causes of handshake pain is Basal Joint Arthritis, which affects the carpometacarpal (CMC) joint at the base of the thumb. The handshake requires a forceful gripping motion that pushes the thumb bone (metacarpal) against the wrist bone (trapezium), causing painful friction if the protective cartilage has worn away. Pain from this condition is typically localized deep within the fleshy part of the thumb base and is intensified by any pinching or sustained gripping.

Another common source of pain is De Quervain’s Tenosynovitis, an inflammatory condition affecting the two tendons that run along the thumb side of the wrist. The sheaths surrounding these tendons become thickened and restricted, making the sliding motion difficult and painful. The subtle, yet unavoidable, wrist twisting or rotational component of the handshake motion sharply aggravates this inflammation, causing pain that often radiates up the forearm.

Pain originating from a Trigger Finger or Trigger Thumb may also be exacerbated by the firm grip of a handshake. This condition involves the inflammation and swelling of a tendon sheath, which prevents the flexor tendon from gliding smoothly through its pulley system. While the pain is often felt when flexing or extending the digit, the sudden, compressive force of a strong grip can cause a painful catch or pop within the palm.

In some cases, the pain felt during a handshake is not originating directly in the hand but is instead a form of referred pain. Conditions like Carpal Tunnel Syndrome or lateral epicondylitis, often known as tennis elbow, can generate pain that is perceived in the wrist or hand when pressure is applied. The compression of the median nerve in carpal tunnel or the tension on the extensor tendons in the elbow can be momentarily intensified by the application of external force during the greeting.

How the Handshake Movement Causes Pain

The handshake is a unique biomechanical event involving intrinsic gripping power and extrinsic compression. Grasping another person’s hand requires the flexor tendons and intrinsic hand muscles to generate a powerful grip, placing immediate strain on structures like the CMC joint and flexor tendon sheaths.

The pressure component is external and often unpredictable, as the other person applies force directly to the strained tissues. Inflamed or arthritic joints, which are protected in daily movements, are suddenly compressed, leading to an acute spike in discomfort.

The social convention also introduces a slight rotational or twisting component as the hands are clasped. This subtle motion involves supination and pronation of the wrist, which specifically irritates inflamed tendon sheaths, such as those affected by De Quervain’s tenosynovitis.

Immediate Self-Care and Relief Measures

Following an acutely painful handshake, focus on reducing inflammation. Applying the RICE protocol—Rest, Ice, Compression, and Elevation—is the first practical step. Applying a cold pack to the painful area, such as the thumb base or wrist tendons, for 10 to 15 minutes can dull pain signals and reduce localized swelling.

Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen can manage short-term pain and target the inflammatory response. These medications temporarily inhibit the body’s production of pain-causing chemical messengers. They are symptomatic treatments and should not be relied upon for extended periods without medical guidance.

For temporary stabilization, a soft splint or brace can immobilize the affected joint or tendon sheath, preventing painful movements. This helps stabilize the thumb for CMC joint pain or limits wrist movement for tendonitis.

When anticipating a social interaction, offer a looser, more relaxed grip or use the non-dominant hand. If a painful handshake is unavoidable, keep the hand and wrist as straight and rigid as possible to minimize rotational stress. Offering a fist bump or a high-five are effective and socially acceptable alternatives that significantly reduce compressive and rotational forces.

Medical Evaluation and Long-Term Solutions

If hand pain persists beyond a few days of self-care, or if it involves a loss of grip strength or daily function, seek a professional medical evaluation. A physician, often a hand specialist or orthopedic surgeon, will conduct a physical examination, including specific tests to isolate the pain source. For example, the Finkelstein test confirms De Quervain’s Tenosynovitis by stretching the affected tendons.

Imaging studies, such as X-rays, assess bony structures, confirm arthritis, or rule out stress fractures. Establishing an accurate diagnosis is the foundation for successful long-term management, which often begins with targeted physical or occupational therapy.

Physical therapy restores mobility and strengthens supporting muscles. A therapist prescribes specific hand and wrist exercises, such as range-of-motion movements followed by strengthening activities. These exercises improve the dynamic stability of the hand and wrist, making them more resilient to external forces.

If conservative measures fail, advanced medical treatments are considered. Corticosteroid injections deliver potent anti-inflammatory medication directly into the site of inflammation, such as a tendon sheath or arthritic joint. This can provide relief lasting several months, allowing rehabilitation to progress.

For severe, unrelenting pain or conditions that significantly impair function, surgical intervention may be necessary. Options range from a simple tenosynovectomy to release a restricted tendon sheath, to joint reconstruction or replacement for advanced basal joint arthritis. These procedures are reserved for cases where all other treatments have failed.

Preventing recurrence requires long-term attention to ergonomics and maintenance. Modify the workspace to ensure proper wrist alignment while typing or using a mouse to minimize tendon strain. Incorporating a daily regimen of hand and wrist warm-up exercises keeps tissues supple and reduces the likelihood of discomfort.