Why Does Colon Cancer Cause Constipation?

Colon cancer begins in the large intestine, specifically the colon, due to the uncontrolled growth of cells forming a tumor. Constipation refers to infrequent or difficult bowel movements, often characterized by hard, dry, or lumpy stools. This article explores how colon cancer can lead to constipation.

Understanding Bowel Function

The large intestine, or colon, plays an important role in the final stages of digestion. After most nutrients are absorbed in the small intestine, remaining liquid waste enters the colon. The colon absorbs water and electrolytes, solidifying waste into stool.

Muscular contractions, known as peristalsis, propel stool through the colon towards the rectum for elimination. Normal bowel frequency varies, generally ranging from three bowel movements per day to three per week. Constipation occurs when stool moves too slowly, allowing too much water to be absorbed, resulting in hard and difficult-to-pass stools.

Direct Tumor Effects on Bowel Movement

A colon tumor can directly impede stool passage. As a tumor grows within the colon, its physical presence can act as a blockage, narrowing the internal passageway. This physical obstruction reduces the lumen, making it harder for waste to move through.

Tumors can also interfere with the normal muscular contractions of the colon. The tumor’s presence can disrupt the coordinated muscle movements that push stool along. This impaired peristalsis slows waste transit, leading to increased water absorption and harder stools.

The tumor can cause localized inflammation and swelling within the colon. This inflammatory response can further narrow the colon’s passageway. Swelling adds to the mechanical barrier, making it even more challenging for stool to pass.

Other Constipation Contributors

Beyond direct physical obstruction, several other factors can contribute to constipation in individuals with colon cancer. Tumors can affect nearby nerves, disrupting signals that coordinate bowel movements. This nerve involvement can lead to irregular or ineffective contractions.

Patients may experience dietary changes, such as reduced fiber intake. A diet low in fiber and fluids can result in harder, drier stools, which are more difficult to pass. Certain pain medications, particularly opioids, commonly prescribed for cancer patients, are well-known for causing constipation by slowing gut motility.

Decreased physical activity can also slow bowel function. Reduced mobility means less stimulation for the digestive system, contributing to sluggish bowel movements. Patients may not drink enough fluids, leading to dehydration, which makes stools harder and more difficult to pass.

When to Seek Medical Attention

While constipation is a common issue, persistent changes in bowel habits, especially when accompanied by other symptoms, warrant medical evaluation. A noticeable and lasting change in bowel habits, such as new onset constipation or alternating constipation and diarrhea, should prompt a visit to a doctor.

The presence of blood in the stool is a significant warning sign that requires immediate medical attention. Unexplained weight loss is another symptom that should be investigated. Persistent abdominal pain, cramps, or discomfort that does not resolve should also be evaluated by a healthcare professional. Unexplained fatigue or weakness that interferes with daily activities may signal an underlying issue. Seeking timely medical attention for these symptoms is important for early diagnosis and appropriate management.