A burning sensation in the throat or chest after taking clindamycin is a common and often concerning side effect. This article explains why clindamycin causes irritation, outlines practical steps to prevent or minimize it, and addresses when to seek medical attention.
Understanding the Irritation
The burning sensation experienced after taking clindamycin stems from its chemical properties and how it interacts with the delicate lining of the esophagus. When dissolved, clindamycin has a low acidic pH, which can directly injure the esophageal wall. This caustic property can lead to a chemical burn if the medication remains in contact with the esophageal lining for too long.
This type of drug-induced injury to the esophagus is medically termed “pill esophagitis.” Clindamycin is a known contributor to this condition, alongside other medications like certain antibiotics and bisphosphonates. Damage typically occurs when the pill lodges or dissolves prematurely in the esophagus rather than passing quickly and completely into the stomach.
If the pill lingers, it can cause direct irritation, leading to inflammation (esophagitis) and, in some cases, the formation of ulcers. These ulcers can appear as localized, solitary, or multiple lesions with sharply defined borders. The middle and distal portions of the esophagus are common sites for these injuries.
Practical Strategies for Relief
To prevent or minimize the burning sensation from clindamycin, proper administration techniques are important. Always take clindamycin capsules with a full glass of water (6 to 8 ounces). This ample fluid helps ensure the pill travels swiftly down the esophagus and into the stomach, reducing the chance of it lodging and causing irritation. Insufficient water intake is a common factor that slows the medication’s progression.
After swallowing the medication, it is important to remain in an upright position for at least 30 to 60 minutes. This means avoiding lying down, even for short naps, as lying flat can allow the pill to linger in the esophagus and increase the risk of irritation. Staying upright utilizes gravity to aid the pill’s passage.
Taking clindamycin with food can also be a helpful strategy. Consuming it with a meal can help reduce general stomach upset and heartburn. The presence of food can buffer stomach acids and provide additional bulk to assist the pill in its transit. These steps facilitate the rapid and complete passage of the pill into the stomach, thereby protecting the esophageal lining from its caustic properties.
When to Contact a Healthcare Provider
While throat irritation from clindamycin can often be managed with proper administration, certain symptoms warrant medical attention. Seek medical advice if you experience severe chest pain, particularly behind the breastbone, as this can be a sign of significant esophageal irritation or injury. Pain with swallowing (odynophagia) or difficulty swallowing (dysphagia) are also important symptoms to report. Odynophagia can be severe enough to make swallowing even saliva painful.
Contact your doctor if symptoms persist or worsen despite following recommended administration techniques. Be aware of any signs of bleeding, such as black or tarry stools, or vomiting blood, which could indicate a more serious esophageal injury. New or worsening heartburn should also be discussed with a healthcare provider.