Why Do You Start Sweating When You’re Sick?

Sweating heavily while ill is a common experience. This symptom, especially when accompanying a fever, is not a sign of failure but an indication that a natural defense mechanism is working. Sweating is the body’s primary tool for cooling down after its internal temperature has been deliberately elevated to fight infection.

How Illness Resets the Body’s Thermostat

The regulation of body temperature is overseen by the hypothalamus, a small region in the brain that acts like the body’s thermostat. When an infection occurs, the immune system releases chemical messengers known as pyrogens. These pyrogens can be either substances from the invading pathogen or proteins produced by the body’s own immune cells.

These chemical signals travel to the hypothalamus and trigger the production of prostaglandin E2 (PGE2), which effectively resets the body’s temperature set point upward. The body suddenly perceives its normal temperature as too low and initiates mechanisms to raise its core heat to match the new, higher setting. This is why a person may experience chills or shivering while their temperature is actively rising, as the body attempts to generate more heat and conserve it through vasoconstriction. This elevated temperature, or fever, is a controlled response designed to create an unfavorable environment for viruses and bacteria while also enhancing the function of immune cells.

The Role of Sweating in Fever Resolution

Sweating typically appears during the final stage of a fever, known as defervescence or “the fever breaking.” Once the infection is controlled, the production of pyrogens subsides. This signals the hypothalamus to reset the temperature set point back down to its normal range.

Since the body is now significantly warmer than the lower set point, it must actively shed excess heat to cool down. The body accomplishes this by widening blood vessels (vasodilation), which brings warm blood closer to the skin’s surface. Heat dissipation is dramatically accelerated by the production of sweat, which cools the skin as it evaporates. Profuse sweating is a positive sign, indicating that the body is successfully regulating its temperature and the fever is resolving.

When Sweating Requires Medical Attention

While heavy sweating is a normal part of fever resolution, excessive fluid loss can quickly lead to dehydration. Dehydration is characterized by symptoms such as extreme thirst, dizziness, and producing dark-colored urine in small amounts. Replenishing fluids and electrolytes is paramount to support the body’s recovery, as severe dehydration can hinder the natural cooling process and cause the temperature to rise again.

It is important to watch for concerning symptoms that accompany sweating, especially if the sweating is sudden, unexplained, or not related to a fever that is breaking. This may include cold sweats paired with chest pain, shortness of breath, or confusion, which could signal a medical emergency. Additionally, persistent or severe night sweats that occur for weeks without an apparent acute infection should be discussed with a healthcare provider, as they may indicate an underlying condition.