Why Do We Get Stuffy Noses When Sick?

The feeling of a blocked or stuffy nose, known medically as nasal congestion, is one of the most common and uncomfortable symptoms experienced during an illness. This sensation is not simply caused by excess mucus; rather, it is a complex biological defense mechanism involving an intricate chain reaction within your nasal passages. Understanding this process requires looking at the immune response, the physical changes in the nasal tissue, and the protective purpose of the resulting fluid.

The Body’s Initial Response to Illness

When a virus, such as a cold or flu, enters the nasal cavity, the body’s immune system quickly identifies the foreign invader. This detection triggers specialized immune cells to release a cascade of chemical messengers into the local tissue. These signaling molecules, which include compounds like histamine and kinins, act as the immune system’s initial call to action.

These chemicals are designed to initiate inflammation, which is the body’s first line of defense against infection. The swift release of these mediators is necessary to prepare the nasal lining for the fight against the invading pathogen. This chemical signaling sets the stage for the physical changes that ultimately result in the sensation of a stuffy nose.

How Swelling Causes Nasal Blockage

The main reason for the feeling of being blocked is the physical swelling of the nasal tissue itself. The chemical signals released by the immune system cause the blood vessels lining the inside of the nose to widen, a process called vasodilation. This widening drastically increases blood flow to the area, bringing a rush of immune cells to the site of infection.

The majority of this swelling occurs in structures called turbinates, which are highly vascular shelves of bone and tissue that protrude into the nasal cavity. Since the turbinates contain many small blood vessels, they quickly become engorged with the increased blood volume. This rapid engorgement causes the tissue to expand, physically restricting the narrow passage and making it difficult to breathe.

The Function of Increased Mucus Production

Alongside the swelling of the nasal tissue, the inflammatory response also causes the production of excess mucus. The increased blood flow and chemical signals make the walls of the capillaries more permeable. This increased permeability allows fluid and proteins from the bloodstream to leak out of the vessels and into the nasal cavity, a fluid known as transsudate.

This leaked fluid mixes with the existing mucus produced by the submucosal glands, resulting in the thin, runny discharge often associated with being sick. The biological purpose of this excess, thinner mucus is defensive. It acts as a physical barrier, trapping the viruses and bacteria and then flushing them out of the nasal passages.