Why Do My Hands Feel Like They Are on Fire at Night?

Decoding the Burning Sensation

A burning sensation in the hands, particularly at night, can be a distressing experience, often described as a feeling of intense heat, tingling, or even sharp pain. This symptom can significantly disrupt sleep and daily life, prompting many to seek understanding about its origins. This common complaint stems from specific biological processes within the body.

The sensation of burning originates from the intricate network of sensory nerves in the hands and arms. When these nerves are irritated, inflamed, or damaged, they send abnormal signals that the brain interprets as a burning feeling, even without an external heat source. This misfiring of nerve pathways is a fundamental mechanism behind neuropathic pain.

Nerve dysfunction, broadly termed neuropathy, can manifest as various unusual sensations, including burning. This occurs when nerve fibers are compromised, altering signal transmission. Affected nerves can generate spontaneous signals or become hypersensitive to normal stimuli.

Underlying Conditions Causing Nighttime Hand Symptoms

Several conditions can cause burning hands at night. Nerve compression is a common cause, where physical pressure disrupts nerve function. Carpal Tunnel Syndrome (CTS) is a primary example, involving the median nerve in the wrist. Swelling or inflammation can compress this nerve, leading to burning, numbness, and tingling in the thumb, index, middle, and part of the ring finger.

Peripheral neuropathies involve nerve damage outside the brain and spinal cord, often causing burning. Metabolic disorders like diabetes are frequent culprits; high blood sugar damages nerve-supplying blood vessels, leading to diabetic neuropathy. This impairs nerve function, causing pain and burning, often in the extremities. Nutritional deficiencies, especially B vitamins (B12, B6, folate), are also crucial for nerve health. Inadequate levels can cause nerve degeneration and neuropathic symptoms.

Autoimmune conditions are another cause, where the immune system attacks peripheral nerves, causing inflammation and damage that leads to burning pain. Toxic exposures, such as certain medications (e.g., chemotherapy drugs) or chronic alcohol abuse, can also directly injure nerve cells, resulting in toxic neuropathy with burning and numbness. Inflammatory conditions like arthritis can indirectly affect nerves through localized inflammation that irritates or compresses nearby structures.

Small fiber neuropathy (SFN) affects small nerve fibers in the skin that transmit pain and temperature. Damage to these fibers causes intense burning, tingling, and sharp pains, often without affecting larger nerves for strength and reflexes. SFN mechanisms vary, including metabolic, autoimmune, or idiopathic causes, but all result in characteristic burning sensations, often worse at rest.

Factors Intensifying Symptoms at Night

Burning sensations in the hands often intensify at night due to physiological and behavioral factors during sleep. Positional compression is a significant contributor, especially for Carpal Tunnel Syndrome. Many sleep with bent wrists, compressing nerves like the median nerve. This prolonged pressure restricts blood flow and irritates the nerve, intensifying burning and tingling that can awaken a person.

Reduced activity and lack of daytime distractions also intensify nocturnal symptoms. During the day, activities divert attention from discomfort. As the body prepares for sleep, external stimuli diminish, increasing awareness of internal sensations. This heightened perception makes burning sensations feel more prominent.

Fluid shifts during recumbency also increase pressure on nerves and tissues. When lying flat, bodily fluids redistribute, potentially accumulating in the extremities. This fluid accumulation can increase pressure within confined spaces, like the carpal tunnel, exacerbating nerve compression and inflammation.

Changes in body temperature and peripheral circulation during sleep also influence nerve sensitivity. Core body temperature slightly decreases, and blood flow alters. These subtle shifts can affect nerve fiber conductivity or pain receptor sensitivity, making nerves more prone to firing abnormal signals. This creates an environment where burning sensations intensify.

Investigating and Addressing the Causes

Investigating burning hands at night starts with pinpointing the underlying cause. A detailed medical history reviews symptom patterns, onset, and associated conditions or exposures. A comprehensive physical examination assesses nerve function, muscle strength, and sensory perception in the affected hands, providing objective data on nerve involvement.

Diagnostic tools confirm nerve dysfunction and identify its origin. Nerve conduction studies (NCS) and electromyography (EMG) measure electrical activity of nerves and muscles. These tests detect nerve damage, determine neuropathy type and severity, and pinpoint nerve compression sites, like in Carpal Tunnel Syndrome. Blood tests check for metabolic imbalances (e.g., diabetes), nutritional deficiencies (e.g., vitamin B12), or autoimmune markers.

Addressing burning sensations involves targeting the root cause. For nerve compression, like Carpal Tunnel Syndrome, interventions aim to relieve pressure. This may include wrist splints to maintain a neutral position during sleep, reducing nerve compression. For significant compression, surgical decompression can enlarge the carpal tunnel and alleviate pressure on the median nerve.

When systemic conditions cause burning, management focuses on controlling the underlying disease to prevent further nerve damage and promote healing. For diabetic neuropathy, meticulous blood sugar control through diet, medication, and lifestyle adjustments is paramount. Nutritional neuropathies are addressed with appropriate supplementation to correct deficiencies, allowing nerves to recover. Symptomatic relief may involve medications that modulate nerve pain signals or reduce inflammation.