Why Do Babies Get Blisters on Their Lips?

When a parent notices a small bump or bubble on their baby’s lip, these marks, known as lip blisters, are a common occurrence in infancy. They appear as fluid-filled bumps or small calluses on the mouth’s surface. While the sight can be alarming, they are frequently harmless and a normal physiological response to feeding. However, a small number of cases indicate a more serious underlying cause, making it important to understand the difference between benign and potentially infectious blisters.

The Primary Cause: Friction Blisters

The most frequent explanation for a baby’s lip blister is friction caused by the vigorous action of suckling. These are commonly referred to as “suck blisters,” “nursing blisters,” or “sucking calluses” and are not true medical blisters, but rather a minor toughening of the skin. This response results from the intense vacuum and repeated rubbing necessary to efficiently extract milk from a breast or bottle nipple.

The blister typically appears as a single, clear, or whitish bump, often concentrated on the center of the upper lip. Suck blisters are generally painless and transient, often appearing and disappearing between feedings in the early days of life. They may even be present at birth if the baby was practicing their sucking reflex in the womb.

If these friction blisters persist for several weeks or are recurring, they may signal an underlying issue with the baby’s feeding mechanics. An improper latch or suck pattern can increase friction. Consulting with a lactation specialist can help assess if a minor oral restriction or body tension is contributing to the continued blister formation.

When Blisters Signal Infection

While friction blisters are harmless, a lip blister caused by infection requires attention due to the potential for serious complications in infants. The most concerning infectious cause is the Herpes Simplex Virus Type 1 (HSV-1), the virus responsible for cold sores.

Infectious blisters look different from the benign suck blister, typically presenting as a cluster of small, painful, fluid-filled blisters rather than a single, callus-like bump. These clusters may be found on the lips, around the mouth, or near the eyes. A baby with an infectious blister will often show accompanying symptoms, such as a fever, increased fussiness, or refusal to feed due to pain.

The risk of severe disease is high in a newborn infected with HSV-1, so any suspicion of a cold sore-like lesion warrants immediate evaluation by a healthcare provider.

Other viral infections, such as Hand, Foot, and Mouth Disease (HFMD), can also cause blisters on the lips and inside the mouth. HFMD lesions are usually accompanied by a rash of sores on the palms and soles of the feet. Bacterial infections like impetigo or fungal infections like oral thrush can also present as sores or white patches near the mouth.

Managing Lip Blisters and Seeking Medical Guidance

For the common friction blister, no treatment is necessary. Caregivers should avoid attempting to pop or aggressively treat the area. The best approach is to continue with normal feeding, as the blister will typically resolve on its own as the baby’s mouth strengthens and adapts to the feeding process.

If the skin appears dry or chapped, a small amount of a bland emollient, like expressed breast milk or a safe oil, can be applied to soothe the area. Consistent monitoring of the blister’s appearance is important to ensure it remains a single, non-irritated spot.

Parents should contact a healthcare professional immediately if they observe red flags that suggest an infection or a complication. These warning signs include any sign of a fever, lethargy, or an abrupt refusal to eat or drink.

Further medical guidance is needed if the blisters appear as a cluster, begin to spread beyond the lip area, or look like open, oozing sores. Sores that are near the eyes, or any blisters that do not begin to heal within one to two weeks, also require professional assessment.