Nattokinase is a serine protease enzyme derived from natto, a traditional Japanese food made from fermented soybeans. The fermentation process produces this enzyme, which is known for its fibrinolytic activity. Nattokinase is often promoted as a dietary supplement for supporting cardiovascular health and circulation. Understanding where to purchase this supplement and how to evaluate its quality and safety is important for making an informed choice.
Identifying Reputable Retail Sources
When seeking to buy nattokinase, the source of the purchase can influence the product’s authenticity and quality. Many consumers choose online specialty retailers due to the convenience and wide range of brands they offer. These retailers often provide detailed product information and customer reviews, which can be helpful in the initial selection process.
Brick-and-mortar health stores provide immediate access to products and the benefit of consulting with staff who may offer personalized advice. They generally stock established brands, reducing the risk of encountering counterfeit products. Choosing retailers known for handling other health supplements and maintaining proper storage conditions is advisable.
Purchasing directly from a manufacturer’s website offers the highest assurance of receiving an authentic product. Buying direct removes the intermediary. Reputable manufacturers often provide batch-specific testing results and quality certifications on their own sites.
Critical Factors for Supplement Quality
Evaluating the quality of a nattokinase supplement requires looking beyond the basic ingredient list. The most important measure of the enzyme’s potency is its activity, which is standardized and labeled in Fibrinolytic Units (FUs). Consumers should look for a clearly stated FU count on the label, rather than relying solely on the milligram weight of the capsule content. A common daily dosage in studies often falls within the range of 2,000 to 4,000 FU.
Third-party testing is a verification method that confirms the product contains the stated amount of nattokinase and is free from contaminants. Independent organizations like the United States Pharmacopeia (USP) or NSF International provide seals of approval.
The purity of the ingredients is another consideration, particularly regarding unnecessary fillers, artificial additives, and genetically modified organisms (GMOs). High-quality supplements often use a specific, patented form of nattokinase, such as NSK-SD, a trademarked product standardized for activity and safety. Furthermore, NSK-SD is specifically processed to remove Vitamin K2, which is naturally present in natto and can interfere with certain anticoagulant medications.
Safety Considerations Before Purchase
Before incorporating nattokinase, review your personal health profile and existing medications. Nattokinase acts as a fibrinolytic agent, meaning it may contribute to thinning the blood and breaking down clots. This action can increase the risk of bleeding when taken concurrently with anticoagulant or antiplatelet drugs, such as warfarin or aspirin.
Individuals taking any prescription blood-thinning medication must consult a healthcare professional before starting a nattokinase supplement. The enzyme’s blood-thinning properties also pose a risk for those undergoing surgical procedures, including dental work. It is generally recommended to discontinue the use of nattokinase at least two weeks before any scheduled surgery to minimize potential bleeding complications.
Specific populations should avoid the supplement altogether, including pregnant or nursing individuals due to a lack of reliable safety information. People with pre-existing bleeding disorders or a history of intracerebral hemorrhage should also exercise caution. Consulting a medical provider ensures the supplement is appropriate for individual health circumstances.