Progesterone cream is a hormonal supplement containing progesterone, a naturally occurring hormone. It is often prescribed to support reproductive health, particularly during pregnancy, by supplementing the body’s natural progesterone levels when insufficient. This cream is one of several forms of progesterone supplementation, including oral capsules, injections, and vaginal gels or inserts.
The Role of Progesterone in Pregnancy
Progesterone plays a significant role throughout pregnancy. It prepares the uterine lining (endometrium) for implantation. After implantation, progesterone helps maintain pregnancy by stimulating endometrial glands to secrete nutrients for the early embryo. This hormone also prevents the immune system from attacking the developing embryo and suppresses uterine contractions, avoiding preterm labor.
The corpus luteum initially produces progesterone during the first eight weeks of pregnancy, with the placenta taking over at 8-12 weeks. Supplementation, including progesterone cream, may be prescribed for reasons like luteal phase support, especially in assisted reproductive technology (ART) cycles like IVF. It may also be recommended for those with a history of recurrent miscarriage or at risk of preterm birth, always under medical supervision.
Common Application Areas
Application areas depend on the cream’s formulation and medical advice. Vaginal application is often preferred for pregnancy support due to direct uterine absorption. This allows local action on the uterine lining, benefiting implantation and early pregnancy maintenance. Vaginal progesterone is available as gels and inserts.
For topical skin application, common areas include the inner thighs, inner arms, chest, abdomen, or neck. These areas are chosen for thinner skin, allowing for better absorption. Rotating application sites daily may prevent irritation and ensure consistent absorption. While topical skin application is common for other uses, vaginal application is typically emphasized for pregnancy support.
Guidelines for Proper Application
Proper application is crucial for effectiveness. Wash hands thoroughly before and after each application. Ensure the application area is clean and dry, avoiding lotions or oils that can interfere with absorption.
Dosage is crucial and determined by your healthcare provider. Creams often come with specific applicators, or dosage may be measured in milligrams, typically a pea-sized to nickel-sized amount. Follow prescribed frequency and timing (e.g., once or twice daily at a consistent time) to maintain stable hormone levels.
Gently rub the cream into the selected skin area until fully absorbed (a few minutes). If using a vaginal cream or gel, lying down after application may help with retention. Consistent application, adhering strictly to the prescribed schedule, is important for treatment success.
Important Considerations During Treatment
Be aware of potential side effects during treatment. Common, mild side effects include breast tenderness, nausea, fatigue, mood changes, and local irritation. Some individuals might experience headaches, bloating, or changes in bowel movements.
If a dose is missed, apply it as soon as remembered. However, if it’s almost time for the next dose, skip the missed one and continue the regular schedule. Do not double the dose; consult your healthcare provider for guidance on missed doses.
Proper storage maintains stability and effectiveness. Store at room temperature, away from direct sunlight, heat, and humidity. Keep medication out of reach of children and dispose of unused or expired cream properly.
Contact your healthcare provider for severe side effects, allergic reactions (rash, swelling), or any unusual symptoms. Progesterone cream is a prescription medication and must be used under medical supervision.