Estrogen cream is a prescription medication containing the hormone estrogen, typically estradiol. It is applied directly to target tissues to address symptoms related to declining natural hormone levels. This localized therapy aims to improve tissue health without significant absorption into the bloodstream, distinguishing it from systemic hormone therapies.
Primary Application Site: Vaginal Use
The primary and most common site for applying estrogen cream is the vagina. This method directly addresses symptoms associated with the genitourinary syndrome of menopause, a collection of changes in the vulvovaginal and lower urinary tract tissues due to reduced estrogen levels. These changes can include vaginal dryness, burning, itching, and painful intercourse. Applying estrogen cream vaginally helps to restore the thickness and elasticity of the vaginal lining, increasing natural lubrication and improving overall vaginal health.
Estrogen receptors are abundant in the vaginal and urethral areas, making local application highly effective for these specific concerns. This localized approach also helps alleviate urinary symptoms, such as urgency, irritation with urination, and can reduce the frequency of urinary tract infections in postmenopausal individuals.
Applying Estrogen Cream Correctly
Applying estrogen cream correctly is important for its effectiveness and comfort. The cream typically comes with a specialized applicator designed to measure the precise dosage and facilitate insertion into the vagina.
To prepare the applicator, press the plunger all the way down, then screw the open end onto the cream tube. Gently squeeze the tube to fill the applicator to the prescribed dosage line, usually marked in grams. After filling, unscrew the applicator from the tube and replace the cap. For insertion, lie on your back with knees bent and parted, or stand in a comfortable position, then gently insert the applicator into the vagina as far as is comfortable, pushing the plunger to release the cream. Some individuals may find it more comfortable to apply a pea-sized amount of cream with a clean finger, spreading it around the vaginal opening and just inside, ensuring coverage of the urethral area where estrogen receptors are also present. After use, the applicator should be cleaned with mild soap and warm water, then rinsed thoroughly, but not boiled.
Important Usage Tips
The cream should be stored at room temperature, ideally between 59 and 86 degrees Fahrenheit (15 and 30 degrees Celsius), and protected from temperatures exceeding 104 degrees Fahrenheit (40 degrees Celsius). It is important to keep the medication in its tightly closed container, out of reach of children and pets.
If a dose is missed, it should be applied as soon as it is remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped, and the regular dosing schedule resumed; double doses should not be used. Applying the cream at bedtime is often recommended to reduce leakage and allow for better absorption. While some leakage is normal, using tampons or other vaginal products immediately after application to contain the cream is not advised. Wearing a sanitary pad or pantyliner can help protect clothing.
When to Talk to Your Doctor
It is important to discuss any pre-existing medical conditions before starting treatment, as certain health issues may influence the suitability of estrogen therapy. Regular check-ups are also recommended to assess the effectiveness of the treatment and determine if continued use at the current dosage is appropriate.
Contact a doctor promptly if symptoms do not improve or worsen, or if unexpected or bothersome side effects occur. These could include vaginal bleeding or spotting after menopause, new breast lumps, severe headaches, sudden changes in vision or speech, or pain and swelling in the legs. Any unusual vaginal discharge, irritation, or persistent discomfort at the application site also warrants medical attention.