When Was the First Successful Open Heart Surgery?

Open heart surgery involves operating directly on the internal structures of the human heart. This complex procedure, once considered impossible, has significantly advanced healthcare. It treats various heart conditions previously untreatable, improving patient outcomes and extending lives.

Pioneering Efforts and Obstacles

Early attempts at heart surgery faced immense challenges. The heart’s continuous movement and high-pressure blood flow caused rapid blood loss, limiting operating time and visibility. Infection was also a significant concern, as sterile techniques were not yet fully developed. Early 20th-century medicine lacked the physiological understanding and technological tools to safely stop the heart or maintain circulation during repairs. Surgeons considered the heart an untouchable organ, making open-heart procedures seem unattainable for decades.

The Breakthrough Moment

The first widely recognized successful open heart surgery was performed by Dr. F. John Lewis at the University of Minnesota Hospital. On September 2, 1952, Dr. Lewis, assisted by Dr. C. Walton Lillehei, operated on 5-year-old Jacqueline Johnson. The procedure aimed to repair an atrial septal defect, a hole between the upper chambers of her heart.

To create a workable surgical field, Dr. Lewis used induced hypothermia, cooling the patient’s body to approximately 82 degrees Fahrenheit (28 degrees Celsius). This technique slowed metabolic processes, reducing oxygen demand and allowing temporary interruption of blood flow to the heart, known as inflow occlusion. The team had a crucial five to six-minute window for the delicate repair in a relatively bloodless field. The operation succeeded, with the patient recovering fully, marking the first correction of a congenital heart defect under direct vision.

Enabling Technologies and Techniques

The success of the first open heart surgery relied on several medical and technological advancements. Induced hypothermia, refined by researchers like Wilfred Bigelow, extended the safe period for circulatory arrest, allowing surgeons to work on the heart when it was slowed and still.

The heart-lung machine, or cardiopulmonary bypass (CPB), developed by Dr. John Gibbon, was another innovation. Though not used in Lewis’s 1952 surgery, Gibbon’s tireless work culminated in its first successful human use in May 1953. This machine provided external support for circulation and oxygenation, allowing for longer operating times and more complex repairs than hypothermia alone. Advancements in anesthesia also played a role, providing better control over the patient’s physiological state during these procedures.

Establishing a New Medical Frontier

The successful open heart surgery in 1952 validated the possibility of directly repairing defects within the human heart. This event spurred further research and innovation in cardiac surgery. It paved the way for the widespread development and adoption of techniques like cardiopulmonary bypass and cross-circulation, which Dr. Lillehei pioneered shortly after. The success encouraged medical professionals to explore and refine new surgical approaches, leading to the establishment of modern cardiac surgery as a specialized and effective field. This operation opened a new frontier, allowing for the eventual treatment of a vast array of complex congenital and acquired heart diseases.