When to Stop Fortifying Breast Milk

Breast milk fortification is a temporary medical intervention used for infants born prematurely or those with specific medical conditions. This practice involves adding a powdered or liquid supplement, known as a fortifier, to expressed human milk. The goal is to enrich the milk with extra calories, protein, and minerals to support rapid “catch-up growth” and development. This specialized feeding regimen is managed by a medical team until the infant achieves specific physiological and developmental milestones.

Nutritional Goals of Fortified Breast Milk

Unfortified human milk, while optimal for a term infant, does not contain sufficient nutrients to meet the high growth requirements of a very low birth weight infant. Fortifiers are specifically formulated to compensate for this deficit. These supplements significantly increase the concentration of protein, which is necessary for tissue and organ development, and provide extra calories to fuel rapid growth. They also boost the levels of bone-building minerals, particularly calcium and phosphorus, which are often deficient in infants born before their bones have fully mineralized. Achieving optimal early growth is associated with improved long-term neurodevelopmental outcomes.

Key Criteria for Discontinuing Fortification

The decision to discontinue breast milk fortification is individualized and determined by a neonatology or pediatric team based on specific medical and developmental benchmarks. One of the primary indicators is the infant achieving a specific corrected age, which is the chronological age minus the number of weeks the infant was born prematurely. Fortification is typically continued until the infant reaches a corrected age of approximately 37 to 40 weeks.

A major physiological milestone is the infant reaching a predetermined weight threshold, generally in the range of 2,500 to 3,000 grams (about 5.5 to 6.6 pounds). This weight gain must be accompanied by a consistent and stable growth velocity, meaning the infant is steadily gaining weight, length, and head circumference at a healthy pace. The medical team will also transition the infant’s growth monitoring from specialized NICU-based growth charts to standard infant growth charts, such as those from the World Health Organization (WHO) or Centers for Disease Control and Prevention (CDC).

The infant must demonstrate the ability to track along a stable percentile curve on these standard charts without the added nutritional boost. If the infant’s growth velocity remains consistent and adequate for several weeks, it indicates the infant is successfully absorbing and utilizing the nutrients from unfortified milk. The decision is ultimately a clinical judgment that confirms the baby’s organ systems are mature enough to handle the standard nutritional density of human milk alone.

The Process of Weaning and Monitoring Post-Fortification

Once the medical team determines that the infant has met the established criteria, the fortifier is gradually reduced rather than stopped abruptly. This process, known as weaning, is a gentle transition to allow the infant’s digestive system to adapt to the lower caloric density of unfortified human milk. A common approach involves stepping down the concentration of the fortifier, for instance, reducing the milk from 24 calories per ounce to 22 calories per ounce before moving to the standard 20 calories per ounce.

The gradual reduction may also involve fortifying fewer feedings per day, ensuring the infant continues to receive the benefits of human milk while slowly decreasing the added nutritional load. This careful weaning strategy helps prevent any sudden drop in growth velocity and minimizes the risk of digestive discomfort. The period immediately following the cessation of fortification is a time of intensive follow-up care. The medical team will implement close monitoring of the infant’s growth parameters, including weekly or bi-weekly checks of weight, length, and head circumference. Follow-up appointments with the pediatrician are crucial, and sometimes a referral to a pediatric nutritionist may be advised to confirm the infant’s long-term nutritional health.