When to Order Contrast With a CT Scan

A computed tomography (CT) scan uses X-rays and computer processing to create detailed cross-sectional images of the body. Sometimes, a special substance called contrast media is used. This substance helps highlight specific tissues, organs, or blood vessels, making them stand out more clearly. The decision to use contrast depends on the medical question the doctor aims to answer.

Understanding CT Contrast

CT contrast media temporarily change how certain body parts appear on images. These agents absorb X-rays differently from surrounding tissues, making specific structures appear brighter or clearer. This enhancement allows radiologists to better identify abnormalities.

Two primary types of contrast are used: intravenous (IV) and oral. IV contrast, typically iodine-based, is injected into a vein and travels through the bloodstream. It is useful for visualizing blood vessels and enhancing solid organs like the liver, kidneys, and pancreas. Oral contrast, often a diluted solution, is swallowed. This type coats the digestive tract, making the esophagus, stomach, and intestines more visible.

Clinical Scenarios for Contrast Use

Contrast is used when greater clarity is needed to visualize specific structures or conditions. It helps reveal details for accurate diagnosis and treatment planning.

Contrast aids in evaluating vascular issues. It helps assess blood vessels for conditions like aneurysms, bulges in vessel walls, or blockages that restrict blood flow. Contrast can also highlight dissections, where layers of a blood vessel wall separate.

Infections and inflammation are often clearer with contrast. Areas of active inflammation or abscesses, collections of pus, absorb contrast differently than healthy tissue, making them more apparent. This helps pinpoint the exact location and extent of an inflammatory process.

Contrast is also employed in tumor detection and staging. It helps delineate tumors from surrounding healthy tissue, assess their blood supply, and check for cancer spread. For organs like the liver, kidneys, pancreas, or spleen, contrast allows for detailed assessment to identify lesions. In trauma cases, contrast assists in assessing internal bleeding or organ injury, providing rapid information during emergencies.

Important Considerations and Precautions

Healthcare providers carefully consider a patient’s medical history and health status to ensure safety and determine if contrast administration is appropriate.

Kidney Function

Intravenous contrast agents are primarily cleared from the body by the kidneys. Before IV contrast, blood tests are typically performed to measure creatinine levels and estimate glomerular filtration rate (GFR). These tests assess kidney health, as impaired function can increase the risk of contrast-induced nephropathy, a potential kidney injury.

Allergies

Allergies are another important consideration. Patients should inform their healthcare team about any known allergies, especially to previous contrast agents or iodine. Allergic reactions can range from mild symptoms like hives or itching to severe responses like difficulty breathing. Pre-medication with steroids may be considered for individuals with a history of mild reactions.

Pregnancy and Breastfeeding

Pregnancy and breastfeeding also require special attention. Contrast is generally avoided during pregnancy unless medically necessary and benefits outweigh risks to the fetus. For breastfeeding mothers, a brief interruption for 12 to 24 hours after contrast may be recommended, though evidence suggests minimal risk to the infant. Individuals with certain thyroid conditions, particularly an overactive thyroid, may also require specific precautions or alternative imaging methods, as iodine can affect thyroid function.

Medications

Certain medications can interact with contrast agents. Metformin, a medication used for diabetes, is a notable example. Patients taking metformin may be advised to temporarily discontinue the medication before and for a period after the scan to prevent lactic acidosis.

What to Expect During a Contrast CT Scan

Understanding the process of a contrast CT scan can help patients feel more prepared. It involves preparation, the scan itself, and post-scan care.

Preparation often includes specific instructions, such as fasting for several hours before the appointment if intravenous contrast will be used. If oral contrast is required, patients may drink a specific amount of the liquid over a period of time before the scan. This allows the contrast to travel through the digestive system and adequately coat relevant organs.

During the scan, if intravenous contrast is administered, a healthcare professional will insert a small needle into a vein, usually in the arm or hand. Patients may experience a sensation of warmth spreading throughout their body, a metallic taste in their mouth, or a temporary feeling of needing to urinate as the contrast flows through their system. These sensations are generally brief and resolve quickly. For the scan, the patient lies on a movable table that slides into the CT scanner, and it is important to remain still to ensure clear images are obtained.

After the contrast CT scan, patients are typically encouraged to drink plenty of fluids. This helps to flush the contrast material out of the body through the kidneys. Most side effects from contrast are mild and temporary, and the medical team will provide specific post-scan instructions.