When Does Relaxin Hormone Start in Pregnancy?

Hormones orchestrate significant changes in the body during pregnancy, guiding its transformation to nurture a developing fetus and prepare for childbirth. These chemical messengers play distinct roles, offering insight into the remarkable adaptability of the pregnant body.

Understanding Relaxin

Relaxin is a peptide hormone. While present at low levels before pregnancy, its production significantly increases after conception. During pregnancy, its primary sources are the corpus luteum in the ovary and, later, the placenta. This hormone is a key player in the female reproductive system, particularly during the profound physiological shifts of gestation.

When Relaxin Levels Begin to Rise

Relaxin levels begin to rise very early in pregnancy, often around the time of ovulation and potential conception. If pregnancy occurs, its production surges, reaching peak levels during the first trimester, typically around 12 to 14 weeks. The corpus luteum is the initial primary producer of relaxin, supporting the early stages of pregnancy, before the placenta takes over a more prominent role. Even though levels may decrease after the first trimester, relaxin remains present throughout the entire pregnancy.

Key Functions of Relaxin in Pregnancy

Relaxin performs several important physiological functions to support pregnancy and prepare the body for delivery. One of its most recognized roles is the relaxation and loosening of ligaments and joints, particularly those in the pelvis. This increased flexibility in the pelvic area is important for accommodating the growing uterus and facilitating the passage of the baby during childbirth. Relaxin also plays a part in promoting the growth and remodeling of the uterus and cervix. It aids in preparing the uterine lining for implantation and helps prevent early contractions, which contributes to preventing premature birth.

Beyond its effects on the musculoskeletal system, relaxin supports the development of new blood vessels in the uterus and placenta. This process ensures an adequate blood supply to the fetus, accommodating the significant increase in maternal blood volume during pregnancy. The hormone also helps regulate the mother’s cardiovascular and renal systems to adapt to the increased demands for oxygen and nutrients. Evidence suggests relaxin may influence immune modulation, helping prevent the rejection of the developing fetus by the maternal immune system.

Navigating the Physical Effects of Relaxin

The increased laxity in ligaments and joints caused by relaxin can lead to noticeable physical effects for pregnant individuals. Pelvic pain, often referred to as pelvic girdle pain (PGP), is a common experience, affecting the lower back, hips, groin, or pubic area. This discomfort can make activities like walking, climbing stairs, or changing positions challenging. Some individuals may also experience joint instability or a waddling gait due to altered joint mechanics.

Managing these effects involves practical adjustments and supportive measures:
Maintain good posture and body mechanics to reduce strain on loosened joints.
Avoid heavy lifting or movements that aggravate pain, such as wide-legged stances.
Use supportive devices like a pregnancy support belt for pelvic stability.
Engage in gentle, pregnancy-appropriate exercises, such as swimming or prenatal yoga, to strengthen supporting muscles.
Consult a healthcare provider or physical therapist for persistent or severe pain.