What to Do If You Miss a Levothyroxine Dose

Levothyroxine is a synthetic hormone prescribed to individuals with an underactive thyroid gland, a condition known as hypothyroidism. It replaces the natural thyroid hormone, thyroxine (T4), which the body cannot produce sufficiently. Thyroid hormones play a fundamental role in regulating metabolism and energy levels throughout the body. Ensuring consistent daily dosing is important for maintaining stable thyroid function and preventing the return of hypothyroidism symptoms. However, occasionally missing a dose of this medication is a common occurrence that can cause concern for patients.

Addressing a Single Missed Dose

If you miss a single dose of levothyroxine, guidance depends on the time elapsed. If it is still the same day and you remember within a few hours of your usual dosing time, you can typically take the missed dose as soon as you recall. For example, if you normally take it in the morning and remember by midday, taking it then is usually acceptable. This is because levothyroxine has a relatively long half-life, meaning it stays in your system for several days, so a slight delay in one dose typically does not cause a significant drop in hormone levels.

However, if it is almost time for your next scheduled dose, or if more than 10-12 hours have passed since your usual time, it is generally recommended to skip the missed dose entirely. Instead, you should simply take your next dose at its regularly scheduled time. It is important to avoid taking two doses at once to “catch up,” as this can lead to an excess of thyroid hormone and potentially cause symptoms like a rapid heartbeat, nervousness, or insomnia.

Handling Multiple Missed Doses

Missing several consecutive doses of levothyroxine can noticeably impact your thyroid hormone levels. The body’s thyroid hormone reserves may deplete, potentially worsening hypothyroidism symptoms. These symptoms might include increased fatigue, feeling cold, or constipation.

Do not try to “make up” for multiple missed doses by taking several pills at once. This can imbalance thyroid hormones and cause adverse effects. If you have missed two or more doses in a row, or if you are uncertain about how to proceed, contacting a healthcare professional is important. They can provide personalized advice based on your specific situation, including the number of doses missed and your overall health status.

When to Consult a Healthcare Professional

Consult a doctor or pharmacist regarding missed levothyroxine doses in several instances. Seek medical advice if you experience new or worsening hypothyroidism symptoms after missing doses, such as persistent fatigue, weight gain, increased sensitivity to cold, or constipation. These symptoms can indicate that your thyroid hormone levels have become too low.

Contact your healthcare provider if you are uncertain how to manage a missed dose, especially with other health conditions or interacting medications. If you find yourself frequently missing doses, discussing strategies for better adherence with your doctor can be beneficial. Additionally, always consult a professional before making any significant changes to your levothyroxine dosing schedule based on self-assessment. If you feel unwell or have any concerns about your thyroid levels, contacting your care team is always recommended.