What to Do About Heartburn That Won’t Go Away for Days

Heartburn is a burning sensation felt in the chest, behind the breastbone, caused by acid reflux. This occurs when stomach acid flows backward into the esophagus, the tube connecting the throat to the stomach. While occasional reflux is common, heartburn that persists for days suggests a more chronic issue, likely gastroesophageal reflux disease (GERD). When standard methods fail to provide lasting relief, the underlying cause requires focused attention.

Immediate Lifestyle Adjustments for Relief

To reduce reflux episodes, use gravity by elevating the head of your bed six to nine inches. This physical incline prevents stomach contents from flowing upward while you sleep. Elevating the bed is more effective than stacking pillows, which can bend the body and increase abdominal pressure.

Timing meals requires avoiding eating for at least three hours before lying down or going to bed. This allows the stomach adequate time to empty its contents into the small intestine, lowering the volume available to reflux when horizontal. Reducing meal size and eating more slowly also decreases the pressure exerted on the lower esophageal sphincter.

Identifying and eliminating personal trigger foods can significantly reduce the frequency of heartburn attacks. Common offenders that relax the lower esophageal sphincter or increase acid production include fatty or spicy foods, chocolate, peppermint, and acidic items like tomatoes and citrus fruits. Beverages containing caffeine, carbonation, or alcohol are also known to provoke symptoms and should be avoided or severely limited.

Understanding Over-the-Counter Medications

When lifestyle changes are insufficient, over-the-counter (OTC) medications can provide relief. The quickest relief comes from antacids, such as those containing calcium carbonate, which neutralize stomach acid already present. Antacids provide fast relief, often within minutes, but their effect is short-lived, typically lasting only one to three hours.

Histamine-2 (H2) receptor blockers are a longer-acting option that reduces the amount of acid the stomach produces. Medications like famotidine block histamine from binding to acid-producing cells, decreasing acid secretion. H2 blockers are slower than antacids, usually requiring one to three hours, but they provide acid suppression for several hours.

Proton Pump Inhibitors (PPIs)

For chronic or frequent heartburn, the most potent OTC option is the Proton Pump Inhibitor (PPI) class of drugs. PPIs, such as omeprazole, work by irreversibly shutting down the acid-producing pumps in the stomach lining, leading to the strongest and longest-lasting acid reduction. These drugs are intended for frequent heartburn, defined as two or more days a week.

PPIs are not for immediate relief and may take one to four days to reach their full effect. OTC PPIs are specifically recommended only for a 14-day course of treatment. Repeated use or use beyond this period requires consultation with a healthcare provider to ensure safety and proper diagnosis.

Critical Warning Signs Requiring Immediate Care

While persistent heartburn is often related to GERD, certain symptoms signal a complication or non-digestive emergency requiring immediate medical attention. Severe, crushing chest pain, especially if it radiates to the arm, neck, or jaw, can mimic a cardiac event. Any accompanying symptoms like shortness of breath, dizziness, or sweating alongside chest discomfort require emergency evaluation to rule out a heart attack.

Prompt professional care is needed for vomiting blood or passing black, tarry stools, which indicate bleeding within the upper digestive tract. Difficulty swallowing, or the sensation of food getting stuck in the throat, is also a warning sign. This symptom may suggest inflammation, an obstruction, or the development of narrowing (stricture) in the esophagus.

Unexplained weight loss or loss of appetite should prompt an urgent medical consultation. If heartburn symptoms persist continuously for two weeks despite diligent use of OTC medications, a more comprehensive diagnosis and prescription-strength treatment are needed. These indicators move the situation beyond self-treatment and into professional medical management.

Professional Diagnosis of Persistent Reflux

When persistent heartburn exceeds the capabilities of OTC treatment and lifestyle changes, a healthcare professional, often a gastroenterologist, will begin diagnosis. Initial steps involve a thorough review of the patient’s medical history and a physical examination to understand the symptom pattern. If GERD is suspected or complications are a concern, specialized tests are employed to assess esophageal and stomach health.

A common diagnostic tool is an upper endoscopy, also called an esophagogastroduodenoscopy (EGD). During this procedure, a thin, flexible tube with a camera is inserted through the mouth to visually inspect the lining of the esophagus, stomach, and small intestine. The EGD is useful for checking for physical damage, such as inflammation (esophagitis), ulcers, or precancerous changes like Barrett’s esophagus.

Ambulatory pH monitoring is another technique used to precisely measure reflux, often performed using a small, wireless capsule placed in the esophagus. This device records the acidity (pH levels) over 48 to 96 hours, correlating acid exposure with the patient’s symptoms. The results help confirm GERD and determine if the reflux is acidic or non-acidic, which guides the appropriate long-term treatment plan.

Esophageal manometry measures the function and strength of the esophageal muscles and the lower esophageal sphincter. By assessing how well the muscles coordinate to move food, manometry helps identify underlying motility issues that contribute to reflux. These diagnostic steps allow specialists to move beyond simple symptom treatment to address the root causes of the persistent condition.