What Proportion of Adolescents Have Prediabetes?

The rise of prediabetes in the adolescent population has become a significant public health challenge in the United States. Historically considered a disease of adulthood, the condition now affects a considerable proportion of younger people, signaling a concerning shift in metabolic health trends. This intermediate stage of impaired glucose control places millions of youth at heightened risk for severe long-term complications. Understanding the current statistics is the first step toward addressing this escalating epidemic.

Defining Prediabetes in Adolescents

Prediabetes is a metabolic condition characterized by blood sugar levels that are elevated above the normal range but are not high enough to meet the diagnostic criteria for Type 2 Diabetes (T2D). This state reflects a decline in the body’s ability to process glucose effectively, often due to insulin resistance, where cells do not respond well to insulin. Clinicians use specific blood tests and thresholds to define this condition in adolescents, using the same standards as for adults.

One common diagnostic measure is the Fasting Plasma Glucose (FPG) test, which measures blood sugar after a period of not eating. A result indicating prediabetes falls between 100 and 125 milligrams per deciliter (mg/dL). The Hemoglobin A1c (HbA1c) test provides an average of blood sugar control over the preceding two to three months. A prediabetes diagnosis is confirmed when the HbA1c level is between 5.7% and 6.4%. These diagnostic criteria are standardized across the medical community.

The Current Prevalence Data

The proportion of adolescents in the United States living with prediabetes is substantial and has shown a clear upward trajectory. Data from the National Health and Nutrition Examination Survey (NHANES) provides the most reliable national snapshot of this trend. An analysis of NHANES data spanning 2005 to 2016 estimated that approximately 18% of adolescents aged 12 to 18 years had prediabetes.

More recent data indicates this prevalence has increased dramatically, raising concerns among public health experts. A 2022 analysis utilizing NHANES data from 2015 to 2018 estimated that the prevalence reached 28.2% among youth aged 12 to 19 years. The most recent federal estimate, based on NHANES data collected between 2017 and 2023, suggests that approximately 32.7% of adolescents aged 12 to 17 years now have prediabetes. This figure suggests that nearly one in every three American adolescents is currently experiencing impaired glucose regulation.

The variability in estimates often depends on the specific diagnostic criteria used and the age range studied, but the trend of increasing prevalence is consistent across all reports. Regardless of the exact number, the data confirms that prediabetes is no longer a rare finding in the youth population and is instead a common metabolic challenge.

Key Demographic and Lifestyle Factors

Prediabetes prevalence is strongly influenced by a combination of modifiable lifestyle factors and non-modifiable demographic risk profiles. The most significant factor driving the rise in prediabetes among adolescents is the concurrent epidemic of childhood obesity. A higher body mass index (BMI) is consistently associated with an increased risk of prediabetes, as excess weight often leads to greater insulin resistance.

Genetic predisposition also plays a role, with a strong family history of Type 2 Diabetes (T2D) being a non-modifiable risk factor. This suggests that a genetic vulnerability interacts with environmental factors to accelerate the onset of metabolic dysfunction. Lifestyle choices further compound the risk, particularly physical inactivity and poor dietary habits.

Adolescents who lead sedentary lifestyles and consume diets high in fat, processed foods, and sugar-sweetened beverages show a higher probability of developing the condition. Prediabetes is not distributed equally across the population. Data show a higher prevalence among certain racial and ethnic groups, including non-Hispanic Black and Mexican American youth, suggesting that socioeconomic and environmental disparities contribute to this disproportionate representation.

Progression and Long-Term Health Implications

A diagnosis of prediabetes in adolescence is a serious finding because it indicates an aggressive disease progression compared to the same condition in adults. Youth with prediabetes experience accelerated deterioration of beta-cell function in the pancreas. This leads to a faster transition to T2D, often occurring within a few years, which is a much shorter timeframe than the typical five to ten years observed in adults.

Even before a full T2D diagnosis, prediabetes carries immediate health risks for young people. The condition is closely associated with markers for early cardiovascular disease, including high blood pressure and dyslipidemia (an abnormal level of fats in the blood). Adolescents with prediabetes often present with elevated triglycerides and other risk factors that increase their lifetime burden of heart disease.

Once T2D develops in youth, the long-term prognosis is often severe, with a high cumulative incidence of complications early in life. Within a decade or two of diagnosis, more than half of young people with T2D may develop serious complications, such as retinopathy, nephropathy (kidney damage), and hypertension. This rapid onset of complications underscores why prediabetes in adolescents requires immediate and focused intervention to prevent severe outcomes.