What Percentage of ALS Patients Are Veterans?

Amyotrophic Lateral Sclerosis (ALS), often called Lou Gehrig’s disease, is a progressive neurodegenerative condition that attacks the nerve cells controlling voluntary muscles. Motor neurons in the brain and spinal cord deteriorate, leading to paralysis and eventual respiratory failure. Research has established a significant link between military service and an increased risk of developing this fatal disease, affecting veterans across all branches and periods of service.

The Disproportionate Rate of ALS in Veterans

Veterans represent more than 16% of the total ALS patient population in the United States. This figure is disproportionately high compared to the veteran population’s size within the general public. Studies consistently show that individuals with a history of military service are diagnosed with ALS at a rate 1.5 to 2 times greater than the rate for the non-veteran population.

This elevated risk has been observed in veterans from conflicts spanning multiple eras, including World War II, the Korean War, the Vietnam War, and the Gulf War. The issue gained attention following the 1990–1991 Persian Gulf War, when ALS appeared at an unexpectedly high rate, particularly among younger veterans. Researchers have documented that the risk is not limited to those who served in combat zones, but extends to all who served during a period of war.

The Legal Recognition: Presumptive Service Connection

The statistical disparity between veteran and non-veteran ALS rates led the Department of Veterans Affairs (VA) to establish a policy of “presumptive service connection” for ALS. This designation means a veteran diagnosed with ALS does not need to provide specific evidence proving the disease was caused by an event during their service.

The VA presumes the connection automatically, provided the veteran meets service requirements, such as serving at least 90 continuous days of active duty. This policy simplifies the claims process and ensures that an ALS diagnosis qualifies the veteran for a 100% disability rating and compensation, regardless of when the condition manifests after discharge.

This designation unlocks a comprehensive support structure, including tax-free monthly disability compensation and full access to VA health care. Veterans with service-connected ALS are also eligible for Special Monthly Compensation for severe disabilities, financial assistance for home and vehicle modifications, and grants for specially adapted housing.

Investigating Service-Related Risk Factors

The scientific community is actively investigating the causes behind the elevated ALS risk among veterans, focusing on unique military exposures. Research highlights exposure to environmental toxins, which service members may encounter in various settings. These potential exposures include heavy metals like lead and mercury, pesticides, and industrial solvents used in cleaning equipment.

Specific deployment conditions are also under scrutiny, such as exposure to particulates from open-air burn pits or chemicals like Agent Orange used in past conflicts. Researchers are exploring the neurotoxic properties of these substances and how they might interact with genetic predispositions to trigger the disease. The role of physical trauma, including traumatic brain injuries (TBI) and extreme physical exertion, is being examined as a potential contributing factor.

While studies have found suggestive links between certain factors, a single, definitive cause for the increased veteran risk has not yet been isolated. The current understanding suggests that ALS in veterans may be the result of a combination of unique occupational and environmental stressors. Ongoing research continues to explore these multifactorial exposures to better understand the mechanism behind the disproportionate prevalence of this disease in the military community.