Uro-Vaxom is a prescription medication used to prevent urinary tract infections (UTIs). It functions as an immunostimulant, enhancing the body’s natural defenses against these common bacterial infections. This approach differs from direct antimicrobial treatments by strengthening the immune system. It is primarily intended for individuals experiencing frequent UTI episodes, seeking to reduce their recurrence.
What Uro Vaxom Is Made Of
Uro-Vaxom is composed of specific extracts derived from Escherichia coli bacteria, the most frequent cause of UTIs. Each capsule contains 6 milligrams of lyophilized bacterial lysate from 18 selected E. coli strains. Lyophilized means freeze-dried, and a lysate indicates broken-down components. These bacterial components are inactivated, ensuring they cannot cause an infection.
The manufacturing process ensures the bacteria are no longer viable, but their structural elements remain intact. These components are standardized for consistent composition and potency. This preparation presents specific bacterial antigens to the immune system without posing an infectious risk.
How Uro Vaxom Works
Upon oral administration, the inactivated bacterial components in Uro-Vaxom are absorbed and interact with the immune system, particularly within the gut-associated lymphoid tissue, such as Peyer’s patches. This interaction triggers an immune response by activating various immune cells, including phagocytes and antigen-presenting cells. These activated cells then mature and migrate to the urinary tract, establishing localized immune readiness.
The medication stimulates both innate and adaptive immune responses. It promotes the production of various cytokines and adhesion molecules, contributing to a rapid defense. It also enhances polyclonal lymphocyte activation, leading to increased levels of specific antibodies, such as secretory immunoglobulin A (IgA) and IgG. These antibodies provide humoral protection within the urinary tract’s mucosal lining.
The activation extends to T-lymphocytes and macrophages, which become better prepared to identify and fight off future invading E. coli bacteria. This heightened immune surveillance and response capacity helps reduce the likelihood of bacterial adhesion and colonization within the bladder and urethra.
Who Uro Vaxom Is For
Uro-Vaxom is primarily prescribed for individuals experiencing recurrent urinary tract infections. This includes patients, particularly women, who have two or more UTIs within a six-month period, or three or more infections within a single year. The medication is considered a preventative measure rather than a treatment for an active infection.
It acts as a prophylactic agent, helping to break the cycle of recurring infections and offering an alternative to continuous antibiotic regimens. The European Association of Urology (EAU) guidelines recommend immunostimulation with Uro-Vaxom as a non-antimicrobial measure against recurrent cystitis. This makes it a consideration for those seeking to reduce their reliance on antibiotics due to concerns like antibiotic resistance or side effects.
Administration and Side Effects
Uro-Vaxom is administered as one capsule daily, preferably taken in the morning on an empty stomach. For preventative treatment, the usual course is for three consecutive months. If used as an additional medication during an acute UTI episode, it is taken alongside conventional antimicrobial therapy until symptoms subside, for a minimum of 10 consecutive days. For children over four years of age who may have difficulty swallowing, the capsule can be opened and its contents mixed with a drink, such as fruit juice.
The medication has a favorable safety profile, with side effects being mostly mild. Common reactions include minor gastrointestinal upsets, such as diarrhea, nausea, or stomach discomfort. Skin reactions like itching, rashes, or redness may also occur. Rarely, a slight fever or swelling of the mouth, ankles, feet, or fingers has been noted.
Individuals with a known hypersensitivity or allergy to any of the medication’s components should avoid its use. While no significant drug interactions have been established, immunosuppressive medications may potentially reduce Uro-Vaxom’s effectiveness. Patients should consult a healthcare provider regarding use during pregnancy or breastfeeding, as limited data exists in these populations.