What Is the Strongest Prescription Lidocaine Cream?

Lidocaine cream is a topical anesthetic that induces localized numbness in the skin. It temporarily reduces sensation, alleviating pain and discomfort without affecting the body systemically.

Highest Available Prescription Strength

The strongest lidocaine cream available by prescription is typically a 5% concentration. It comes in various topical forms, including creams, gels, and ointments. While some 5% lidocaine creams are available over-the-counter, higher concentrations, such as 10% lidocaine cream, are only obtainable through a prescription, often prepared by compounding pharmacies. These higher-strength formulations deliver a more pronounced numbing effect, important for procedures or conditions requiring deeper or more extensive topical anesthesia.

How Lidocaine Works

Lidocaine blocks nerve signals in the skin, preventing pain messages from reaching the brain. It achieves this by stabilizing the neuronal membrane, inhibiting the flow of sodium ions into nerve cells. This action prevents the initiation and conduction of electrical impulses along nerve fibers, effectively numbing the treated area and providing localized relief.

Common Medical Uses

Prescription-strength lidocaine cream is used for various medical conditions and procedures requiring localized pain relief. It is frequently applied before minor medical procedures such as venipuncture (drawing blood), inserting intravenous lines, or small dermatological procedures like wart removal. The cream also provides pain relief for conditions like post-herpetic neuralgia, a type of nerve pain that can occur after shingles. Additionally, it is prescribed to alleviate discomfort from minor burns, insect bites, scrapes, and localized pain associated with hemorrhoids or other anorectal issues.

Obtaining and Using Safely

Obtaining prescription lidocaine cream requires consultation with a healthcare professional to determine the appropriate strength and usage. Proper application techniques are important for effectiveness and safety. The cream should be applied only to intact, healthy skin, avoiding open wounds, broken skin, or mucous membranes, which can increase systemic absorption.

The amount of cream, duration of application, and whether to cover the area with a bandage depend on the specific product and medical procedure. Using more than the recommended amount, applying it over large skin areas, or covering it with heat or occlusive dressings can lead to increased absorption into the bloodstream. Excessive systemic absorption can result in adverse effects, including dizziness, confusion, drowsiness, vision problems, or ringing in the ears. More serious, though rare, side effects can include a blood disorder called methemoglobinemia. Therefore, medical supervision is essential to minimize risks and ensure safe and effective use.