What Is the Difference Between Pulmonary and Systemic Circulation?

Blood circulation is the body’s transportation system, continuously moving blood to deliver oxygen and nutrients to tissues and organs, and collect waste products like carbon dioxide for removal.

The Pulmonary Pathway

The pulmonary pathway is a specialized circuit designed to oxygenate the blood. This journey begins when deoxygenated blood, returning from the body, enters the right atrium of the heart. From the right atrium, the blood flows into the right ventricle, which then pumps it into the pulmonary artery.

The pulmonary artery branches, carrying this oxygen-poor blood to the lungs. Within the lungs, the blood travels through tiny capillaries that surround microscopic air sacs called alveoli. Here, gas exchange occurs: carbon dioxide diffuses from the blood into the alveoli to be exhaled, and oxygen from the inhaled air diffuses from the alveoli into the blood. The now oxygenated blood collects in the pulmonary veins, which then return it to the left atrium of the heart, completing the pulmonary circuit.

The Systemic Pathway

The systemic pathway distributes oxygenated blood and nutrients to the vast network of tissues and organs throughout the body. This circulation begins as oxygen-rich blood, freshly returned from the lungs, enters the left atrium of the heart. The blood then moves into the left ventricle, the heart’s most muscular chamber, which pumps it with considerable force into the aorta. The aorta, the largest artery in the body, serves as the main conduit for distributing oxygenated blood.

From the aorta, blood flows into progressively smaller arteries that branch out to supply every part of the body, eventually reaching tiny capillaries within the tissues. At the capillary level, oxygen and nutrients are delivered to cells, while carbon dioxide and other waste products are picked up. Deoxygenated blood, now laden with waste, returns to the heart through a network of veins, which converge into the superior and inferior vena cavae, ultimately draining into the right atrium to restart the entire circulatory process.

Understanding the Differences

Pulmonary and systemic circulation represent two distinct yet interconnected loops of the cardiovascular system. Their primary difference lies in their purpose: pulmonary circulation focuses on gas exchange in the lungs, while systemic circulation distributes oxygen and nutrients to the body’s tissues and removes waste products. This functional divergence dictates the type of blood carried and the pressure within their respective vessels.

In pulmonary circulation, deoxygenated blood travels from the heart to the lungs, where it picks up oxygen and releases carbon dioxide. Conversely, systemic circulation carries oxygenated blood from the heart to the body, delivering oxygen to cells and collecting deoxygenated blood containing carbon dioxide and other waste products for return to the heart. Pulmonary arteries are unique in carrying deoxygenated blood, while pulmonary veins carry oxygenated blood, which is the opposite of the general rule for arteries and veins in the systemic circuit.

Pulmonary circulation involves the heart, lungs, and then back to the heart, forming a relatively short loop. In contrast, systemic circulation is a much longer circuit, moving blood from the heart to the entire body and then back to the heart. This extensive reach means systemic circulation provides functional blood supply to all body tissue.

Pressure levels vary between the two circulations. Systemic circulation operates under higher pressure than pulmonary circulation. This higher pressure is necessary for the systemic circuit to overcome greater resistance and pump blood effectively over longer distances and against gravity to reach all body tissues. The pulmonary circuit, being shorter and having wider vessels, has lower resistance and thus requires less pressure.

The heart chambers involved are specific to each pathway. The right side of the heart (right atrium and right ventricle) manages the pulmonary circulation, pumping deoxygenated blood to the lungs. The left side of the heart (the left atrium and left ventricle) is responsible for the systemic circulation, ejecting oxygenated blood to the rest of the body.