What Is the Difference Between Fungus and Bacteria?

Microorganisms are tiny living things, too small to be seen without a microscope, that play important roles in diverse ecosystems. Fungi and bacteria represent two distinct categories within this microbial world, sharing their small size but differing fundamentally in their biological makeup and life processes.

Fundamental Biological Differences

Their cellular organization is a primary distinction. Bacteria are prokaryotes, meaning their cells lack a membrane-bound nucleus and other specialized compartments (organelles). In contrast, fungi are eukaryotes, possessing a more complex cellular structure with a defined nucleus and various membrane-bound organelles.

Bacteria are generally much smaller (0.5 to 5 micrometers), while fungi are usually larger (2 to 10 µm). Their cell walls, an outer protective layer, also differ significantly. Bacterial cell walls are primarily peptidoglycan, while fungal cell walls are mainly chitin and glucans.

Their basic structures also differ. Bacteria commonly exhibit three main shapes: spherical (cocci), rod-shaped (bacilli), and spiral (spirilla). Fungi often grow as thread-like filaments called hyphae, forming a network (mycelium), though some, like yeasts, are single-celled organisms.

How They Obtain Nutrients and Reproduce

Bacteria acquire nutrients in various ways. Some are autotrophs, producing their own food through photosynthesis or chemosynthesis. Many are heterotrophs, absorbing organic compounds from their surroundings. This versatility allows them to thrive in diverse environments.

Fungi are exclusively heterotrophs. They secrete digestive enzymes onto organic matter, breaking down complex molecules into simpler ones, which are then absorbed. Fungi can be saprophytes (feeding on dead organic material), parasites (living on or in other organisms), or symbionts (forming mutually beneficial relationships).

Bacteria primarily multiply through rapid asexual binary fission, where a single cell divides into two identical daughter cells. While sexual reproduction does not occur, they can exchange genetic material through conjugation, transformation, and transduction, contributing to diversity. Fungi exhibit more complex reproductive methods, using both asexual and sexual reproduction. Asexual reproduction can occur through budding (in yeasts), fragmentation, or spore production, a major means of dispersal. Sexual reproduction also typically involves spore formation.

Their Roles in Nature and Health

Both fungi and bacteria are significant decomposers, breaking down dead organic matter. This process is important for nutrient cycling, releasing essential elements like carbon, nitrogen, and phosphorus back into the environment for other organisms. Fungi, with their extensive hyphal networks, are effective at breaking down tough materials like wood.

Fungi and bacteria also engage in symbiotic relationships. For instance, beneficial bacteria reside in the human gut, aiding digestion. Mycorrhizal fungi form associations with plant roots, enhancing nutrient uptake. Lichens are another example, representing a partnership between fungi and algae or cyanobacteria.

From a health perspective, both can cause infections. Bacterial infections (e.g., strep throat, UTIs) are treated with antibiotics. Fungal infections (e.g., athlete’s foot, yeast infections) require antifungal medications. Their fundamental biological differences, particularly distinct cell structures, explain why different medications are needed. Beyond their roles as pathogens, these microorganisms are valuable in industry, contributing to food production (e.g., yogurt, cheese, bread, beer), pharmaceutical synthesis (e.g., insulin), and bioremediation.