What Is the Best Anti-Inflammatory for Shoulder Pain?

Shoulder pain often arises from inflammation, the body’s natural response to injury or irritation. This can affect structures like tendons, muscles, and the fluid-filled sacs known as bursae within the shoulder. Conditions such as rotator cuff tendinitis, bursitis, and arthritis are common culprits, causing swollen and painful tissues. Anti-inflammatory medications are frequently used to manage this pain by targeting the underlying inflammation.

Understanding Anti-Inflammatory Medications

Anti-inflammatory medications reduce the body’s inflammatory response. They primarily work by inhibiting the production of prostaglandins, hormone-like compounds central to causing inflammation, pain, and fever. By blocking the enzymes responsible for prostaglandin synthesis, these medications alleviate symptoms.

The two main categories of anti-inflammatory drugs are Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and corticosteroids. NSAIDs, such as ibuprofen and naproxen, interfere with cyclooxygenase (COX) enzymes, which are involved in prostaglandin production. Corticosteroids are potent anti-inflammatory agents that mimic hormones naturally produced by the adrenal glands, suppressing a broad range of inflammatory pathways.

Over-the-Counter Options for Shoulder Pain

For shoulder discomfort, over-the-counter (OTC) anti-inflammatory options are a common starting point. Oral NSAIDs like ibuprofen and naproxen are frequently chosen. Ibuprofen is typically taken in doses of 200-400 mg every 4-6 hours, while naproxen is usually taken as 220 mg every 8-12 hours. These medications work systemically to reduce inflammation and pain throughout the body.

Topical anti-inflammatory creams and gels can be applied directly to the skin over the affected shoulder. These products, often containing ingredients like diclofenac, allow local absorption, potentially minimizing systemic side effects. Topical NSAIDs are useful for localized pain, providing targeted relief. Always follow the specific directions on the product packaging for proper dosage and application.

Prescription and Other Anti-Inflammatory Approaches

When OTC options are insufficient, healthcare providers may prescribe stronger anti-inflammatory medications. Stronger oral NSAIDs, such as celecoxib, may be prescribed. Celecoxib is a selective COX-2 inhibitor, meaning it primarily targets the enzyme associated with inflammation, potentially reducing some gastrointestinal side effects compared to non-selective NSAIDs.

Corticosteroid injections, often called cortisone shots, are a direct anti-inflammatory treatment for shoulder pain. These injections deliver a concentrated dose of medication directly into the inflamed area, such as a bursa or tendon sheath. This localized delivery can provide rapid pain relief by reducing inflammation at the source. They are typically considered when oral medications or physical therapy have not yielded sufficient improvement.

Important Considerations for Anti-Inflammatory Use

While anti-inflammatory medications are effective for shoulder pain, their use requires careful consideration due to potential side effects. Oral NSAIDs, whether over-the-counter or prescription, can cause gastrointestinal issues like stomach upset, ulcers, or bleeding. Long-term or high-dose use may also pose risks to kidney function and cardiovascular health.

Individuals with pre-existing conditions, such as kidney disease, heart disease, or a history of stomach ulcers, should use caution or avoid certain anti-inflammatory medications. Do not exceed recommended dosages, as this can increase the risk of adverse effects without improving pain relief. Consulting a healthcare professional is advisable for persistent shoulder pain, before starting any new medication, or for personalized medical guidance.