What Is RLQ Pain and When Is It Serious?

Abdominal pain is often localized by dividing the abdomen into four quadrants centered at the navel. Pain focused in the Right Lower Quadrant (RLQ) can signal both minor issues and serious medical conditions. Understanding the organs situated here is the first step toward determining the cause. Because of the potential for urgent underlying problems, RLQ pain requires careful evaluation.

Defining the Right Lower Quadrant

The Right Lower Quadrant is the area of the abdomen below the navel and to the patient’s right. This region is a crucial anatomical landmark because it houses several distinct organs from multiple systems. The contents of the RLQ include the appendix, a small tube attached to the large intestine, and the cecum, the beginning of the large intestine where it meets the small intestine.

The right side of the urinary tract is also represented, as the lower part of the right ureter passes through this area. In biological women, the RLQ also contains the right ovary and the right fallopian tube. Discomfort originating from any of these structures, including the surrounding blood vessels, muscles, and nerves, may be perceived as RLQ pain.

Common and Serious Causes of RLQ Pain

The most common cause of acute RLQ pain is appendicitis, which is inflammation resulting from the appendix becoming obstructed. This blockage leads to increased pressure, restricted blood flow, and bacterial overgrowth. Pain classically begins as vague discomfort around the navel before migrating and localizing to the RLQ over several hours. The resulting irritation of the abdominal lining (peritoneum) causes sharp, localized pain. Appendicitis is a surgical emergency because if untreated, the appendix can rupture, leading to widespread abdominal infection.

Another condition producing severe RLQ pain is a kidney stone passing from the right kidney into the right ureter. This pain, known as renal colic, is characterized by intense, fluctuating waves that radiate from the back or side down toward the groin and RLQ. The pain results from the stone blocking urine flow and causing spasms in the ureter’s muscular wall.

Inflammatory Bowel Disease (IBD), particularly Crohn’s disease, frequently affects the terminal ileum, the last section of the small intestine located in the RLQ. Chronic inflammation here can cause recurrent RLQ pain, sometimes mimicking appendicitis. Other issues, such as an inguinal hernia, manifest when a section of the intestine pushes through a weakness in the lower abdominal wall. A hernia causes a painful bulge that requires urgent attention if the trapped tissue loses its blood supply.

Causes Specific to Biological Sex

The location of reproductive organs requires considering conditions unique to biological women and men when diagnosing RLQ pain. For women of reproductive age, pain can originate from the right ovary or fallopian tube. A common source is an ovarian cyst, a fluid-filled sac that causes sharp or dull pain if it grows large or ruptures.

A more urgent situation is ovarian torsion, where the ovary twists around its supporting ligaments, cutting off its blood supply. This twisting causes sudden, severe pain and requires emergency surgery. Ectopic pregnancy, where a fertilized egg implants outside the uterus (often in the fallopian tube), also presents with RLQ pain and vaginal bleeding, demanding immediate medical intervention.

Pelvic Inflammatory Disease (PID) is an infection of the reproductive organs that can localize pain to the RLQ. This infection often results from sexually transmitted bacteria and may involve fever, abnormal vaginal discharge, and pain during intercourse.

For biological men, RLQ pain can sometimes be referred pain from conditions affecting the testicles. Testicular torsion, the twisting of the spermatic cord, causes severe scrotal pain that can radiate to the lower abdomen. This is a time-sensitive emergency requiring prompt surgical correction to restore blood flow. Similarly, epididymitis, inflammation of the coiled tube at the back of the testicle, can present with referred RLQ pain along with scrotal swelling and tenderness.

When to Seek Immediate Medical Attention

Recognizing specific warning signs, often called “red flags,” is paramount in determining when RLQ pain signifies a medical emergency. Seek immediate medical attention if you experience any of the following symptoms:

  • The pain is sudden and severe, or the worst pain you have ever experienced.
  • Pain is accompanied by a high fever or chills, suggesting a significant infection or inflammation (e.g., perforated appendix or severe kidney infection).
  • Persistent vomiting or the inability to keep fluids down, which may indicate a bowel obstruction.
  • The presence of blood in your stool or urine.
  • The abdomen feels rigid, hard, or tender to the slightest touch, which is a sign of peritonitis.
  • Inability to pass gas or have a bowel movement, especially when combined with abdominal swelling, signaling an intestinal blockage.
  • Any new or worsening RLQ pain during pregnancy, due to the risk of conditions like ectopic pregnancy or premature labor.

If you experience any of these symptoms, proceed immediately to the nearest emergency room.