What Is Ozempic Neck and What Causes It?

“Ozempic Neck” is an informal term describing the appearance of loose or sagging skin in the neck and lower face that can follow significant weight reduction. This phenomenon is not a side effect of the medication itself, but rather a consequence of the rapid, substantial weight loss that drugs containing semaglutide, such as Ozempic or Wegovy, can facilitate. The term highlights a cosmetic change where the skin, which has been stretched to accommodate greater volume, struggles to retract fully once that underlying volume is gone. This effect is a known factor in any major weight loss journey, whether achieved through diet, surgery, or medication.

Understanding the Physical Causes of Neck Laxity

The physical change known as “Ozempic Neck” stems from a sudden and significant reduction in the subcutaneous fat pads that previously supported the skin. When fat volume diminishes quickly, the overlying skin cannot shrink fast enough to conform to the new, smaller contour. This mismatch between the skin’s surface area and the underlying support structure creates the sagging or wrinkled appearance, particularly noticeable in areas like the neck and jawline where the skin is naturally thin. The skin’s ability to “snap back” is determined by two structural proteins: collagen, which provides firmness, and elastin, which allows the skin to stretch and recoil. Factors like age, chronic sun exposure, and the duration of being overweight can degrade or weaken these fibers, reducing the skin’s inherent elasticity and making it less capable of readapting when rapid fat loss occurs.

Is This Phenomenon Unique to Semaglutide?

The concept of post-weight-loss skin laxity is not new, nor is it exclusive to semaglutide-based medications. The term “Ozempic Neck” gained popularity because these medications enable a faster rate of weight loss for many individuals compared to traditional methods. This rapid volume depletion simply unmasks a phenomenon long observed in patients following bariatric surgery or extreme dieting. The speed and magnitude of the weight loss are the primary contributing factors to skin laxity, rather than a specific chemical property of the drug. The effect seen with semaglutide is essentially an acceleration of the same facial and neck volume loss that occurs with any effective, rapid weight reduction strategy.

Strategies for Minimizing Skin Laxity During Weight Loss

A primary strategy for mitigating skin laxity is to manage the rate of weight loss, if medically appropriate, aiming for a more gradual reduction of approximately 0.5 to 1 kilogram per week. This slower pace can provide the skin’s collagen and elastin fibers more time to adjust and contract to the decreasing volume underneath.

Other strategies focus on supporting skin health and underlying structure:

  • Maintain adequate protein intake (1.2 to 1.6 grams per kilogram of body weight), as protein is a foundational building block for new collagen production.
  • Incorporate regular strength or resistance training to build muscle mass, which provides underlying volume and support that can reduce the appearance of looseness.
  • Ensure proper hydration, as well-hydrated skin retains better overall health and resilience.
  • Use topical skincare ingredients like retinoids or peptides, which encourage collagen synthesis, and apply broad-spectrum sun protection daily to prevent further breakdown of elastic fibers.

Options for Addressing Existing Neck Appearance

For individuals who already exhibit neck laxity, corrective options are categorized as non-surgical or surgical, depending on the severity of the excess skin. Non-surgical treatments are best suited for mild to moderate laxity, focusing on stimulating new collagen production to tighten and firm the skin. These often include energy-based devices such as radiofrequency (RF) microneedling or focused ultrasound treatments, which deliver controlled heat to the deeper layers of the skin. Injectable treatments, such as dermal fillers, may also be used to strategically restore lost volume in the lower face and jawline, improving the contour and subtly lifting the appearance of the neck. For cases involving significant excess skin or prominent neck banding, a surgical procedure like a neck lift (lower rhytidectomy) offers the most dramatic and long-lasting correction by removing redundant skin, tightening underlying neck muscles, and redefining the jawline.