What Is Nightshade Poison? Symptoms and Toxic Compounds

The nightshade family, scientifically known as Solanaceae, includes many commonly cultivated food plants like tomatoes, potatoes, and eggplants. However, this diverse family also contains highly poisonous species that pose significant health risks if ingested. Understanding dangerous nightshades and how to identify potential exposure is important for public safety.

Understanding the Nightshade Plant Family

The Solanaceae family is widespread, with approximately 2,700 species. It includes both staple food crops and plants with potent toxic properties.

Conversely, the family also harbors highly toxic species such as deadly nightshade (Atropa belladonna), bittersweet nightshade (Solanum dulcamara), black nightshade (Solanum nigrum), and jimsonweed (Datura stramonium). The level of toxicity can vary significantly among different species and even within various parts of the same plant. For instance, the ripe berries of some black nightshade varieties might be edible, while their green, unripe counterparts are poisonous.

The Toxic Compounds and Their Effects

The primary toxic compounds in poisonous nightshade plants are alkaloids. Two prominent types are solanine and tropane alkaloids. Solanine is a glycoalkaloid found in plants like potatoes, particularly in green or sprouted parts, and in unripe tomatoes. It disrupts cell membranes and interferes with mitochondrial function, leading to cellular damage and gastrointestinal distress.

Tropane alkaloids, such as atropine, scopolamine, and hyoscyamine, are found primarily in plants like deadly nightshade and jimsonweed. These compounds are anticholinergic, meaning they block the action of acetylcholine, a crucial neurotransmitter in the nervous system. This disruption affects both the central and peripheral nervous systems, leading to a range of systemic symptoms.

Recognizing Symptoms of Nightshade Poisoning

Symptoms of nightshade poisoning depend on the specific toxic compound ingested, the amount consumed, and individual sensitivity. Solanine poisoning often presents with gastrointestinal symptoms, including nausea, vomiting, abdominal pain, and diarrhea. Other symptoms include headaches, dizziness, a rapid pulse, or fever. Severe cases may involve neurological effects like hallucinations, loss of sensation, or paralysis.

Poisoning from tropane alkaloids manifests with a different set of symptoms due to their anticholinergic effects. Signs include a dry mouth, dilated pupils, and blurred vision. Individuals may also experience a rapid heartbeat, fever, confusion, and muscle twitching. Severe cases can lead to hallucinations, delirium, seizures, or a coma.

Emergency Response and Prevention

Suspecting nightshade poisoning requires immediate action. Contacting emergency services or the Poison Control Center is the most important first step. In the United States, the national, toll-free Poison Help line is 1-800-222-1222, connecting callers to local poison centers. When calling, be prepared to provide information such as the person’s age and weight, the name of the plant if known, and the estimated amount ingested.

Preventing nightshade poisoning involves education and careful plant management. Teach children not to consume unknown berries or plants found in gardens or wild areas. Identify and remove any toxic nightshade plants from your yard, especially if children or pets frequent the area. When foraging for wild plants, only consume those you can positively identify as safe and edible.