What Is L. gasseri SBT2055 and What Are Its Benefits?

Lactobacillus gasseri SBT2055 is a specific strain of probiotic, which are live microorganisms that can provide health benefits when consumed in adequate amounts. This strain belongs to the Lactobacillus genus, a group of bacteria known for their role in fermentation. As research into the gut microbiome expands, specific strains like SBT2055 are being examined for their distinct effects. This article explores the identity of L. gasseri SBT2055, its researched benefits, potential mechanisms, and sources.

Understanding L. gasseri SBT2055

Lactobacillus gasseri SBT2055 is a scientifically documented strain of lactic acid bacteria, meaning it produces lactic acid by metabolizing sugars. This species is naturally found in the human digestive and urinary tracts, and SBT2055 was originally isolated from this environment. Its ability to survive in the gut is supported by its tolerance to bile, a digestive fluid hostile to many microorganisms.

The effects of probiotics are strain-specific. The health implications associated with L. gasseri SBT2055 cannot be attributed to other Lactobacillus gasseri strains or the genus as a whole. Each strain has unique genetic characteristics that dictate its functions within the host’s body. Some scientific sources may also refer to this strain as LG2055.

This strain was recently reclassified as Lactobacillus paragasseri SBT2055, reflecting a more precise scientific understanding of its genetic makeup. This change does not alter the historical research findings associated with it. For consumers, it is often still marketed and recognized by its original name.

Researched Health Implications of SBT2055

Research on L. gasseri SBT2055 focuses on metabolic health and body composition. Studies link this strain to reductions in body weight and adipose (fat) tissue, particularly abdominal fat. In clinical trials, participants consuming fermented milk with SBT2055 showed decreases in abdominal visceral fat, waist circumference, and body weight compared to placebo groups.

SBT2055 also appears to influence the immune system. Oral administration has been found to increase the production of Immunoglobulin A (IgA) in the small intestine of mice. IgA is an antibody involved in the immune function of mucous membranes, suggesting SBT2055 may help support gut-associated immune defenses.

The strain can also modify the intestinal environment. Ingestion is associated with changes in gut microbiota, such as increasing the Lactobacillus genus while lowering bacteria like Staphylococcus. These modifications are believed to contribute to its broader health effects.

How L. gasseri SBT2055 May Function

The health benefits of L. gasseri SBT2055 are thought to arise from several biological activities. One mechanism is its interaction with the immune system. The bacteria can stimulate dendritic cells in the gut to produce signaling molecules like TGF-β. This signaling promotes the production of IgA by B cells, enhancing the gut’s mucosal immune barrier.

Another mechanism relates to its influence on fat metabolism and inflammation. Animal studies show SBT2055 can reduce the expression of genes linked to inflammation in adipose tissue. For instance, it can lower the expression of the Ccl2 gene, which recruits inflammatory macrophages into fat tissue. Mitigating this low-grade inflammation may help improve metabolic conditions.

The strain might also improve intestinal barrier integrity. In mice on a high-fat diet, SBT2055 administration reduced intestinal permeability. A less permeable gut prevents inflammatory substances from passing from the intestine into the bloodstream. This improvement may reduce systemic inflammation and support metabolic health.

Sources and Considerations for L. gasseri SBT2055

Lactobacillus gasseri SBT2055 is available to consumers through specific commercial products. It is found in certain brands of probiotic supplements, in capsule or tablet form. This strain is also used in some fortified fermented dairy products, such as yogurts and probiotic drinks. Product labels will explicitly list Lactobacillus gasseri SBT2055 or LG2055.

Individual responses to a probiotic like SBT2055 can differ based on one’s existing gut microbiome, diet, and health status. Reputable brands that guarantee the potency of live cultures through the expiration date are preferred. The dosage, measured in colony-forming units (CFUs), will be on the product’s packaging.

Before beginning any new supplement, consulting with a healthcare professional is recommended. This is particularly important for individuals with compromised immune systems, serious underlying health conditions, or those who are pregnant or breastfeeding. A provider can offer personalized guidance and determine if a probiotic is appropriate for your health needs.