Juice Plus is a line of dietary supplements made from dehydrated juice powders of fruits, vegetables, and berries. Sold in capsules, chewables, and shake mixes, it’s marketed as a way to bridge the gap between what you eat and what your body needs from produce. The products are distributed through a multi-level marketing (MLM) network rather than traditional retail stores, which means you’ll typically encounter them through an independent distributor rather than on a pharmacy shelf.
What’s Actually in It
Juice Plus comes in three core blends, each built from a different mix of plant ingredients. The Fruit Blend includes apple, peach, cranberry, orange, mango, lemon peel, acerola cherry, pineapple, prune, date, and beet. The Vegetable Blend contains broccoli, parsley, tomato, carrot, garlic, beet, spinach, cabbage, lemon peel, rice bran, and kale. The Berry Blend rounds things out with concord grape, pomegranate, bilberry, blueberry, blackberry, elderberry, raspberry, cranberry, black currant, cocoa, artichoke, and ginger.
Each blend also includes added plant-based vitamins. The company’s manufacturing process works by juicing the whole produce, then dehydrating that juice at low temperatures to create a concentrated powder. The low-temperature step is meant to preserve heat-sensitive plant compounds that would break down under higher processing temperatures.
How It’s Sold
Juice Plus operates as a multi-level marketing company, meaning it relies on independent distributors to sell products directly to consumers. Distributors earn money not only from their own sales but also from the sales of people they recruit into the network. This structure creates a financial incentive for distributors to make enthusiastic, sometimes exaggerated health claims about the products. As McGill University’s Office for Science and Society has noted, individual distributors “have been known to make outlandish claims when it comes to recruiting customers and prospective distributors.”
This doesn’t automatically mean the product is bad, but it does mean the marketing you encounter may overstate what the supplements can actually do. It’s worth separating what distributors say from what published research supports.
What the Research Shows
Juice Plus has more published research behind it than many supplements, though the results are modest rather than dramatic. Short-term studies have found that supplementation with fruit and vegetable concentrates can reduce markers of low-grade inflammation and oxidative stress in various groups of people. Research has also confirmed that the plant compounds in the capsules are absorbed by the body and remain bioavailable, meaning they don’t just pass through your system unused.
Safety studies have reported no negative effects on liver, kidney, or thyroid function in healthy people. However, the existing research is mostly short-term, and longer-term controlled trials are still underway to better understand effects on cardiovascular health and chronic low-grade inflammation in middle-aged and older adults.
One important caveat: no supplement replaces actual fruits and vegetables. Whole produce contains fiber, water, and a complex matrix of nutrients that work together in ways a concentrated powder can’t fully replicate. Juice Plus delivers some of the plant compounds found in produce, but it strips away the fiber and most of the bulk that makes whole food beneficial for digestion, blood sugar regulation, and satiety.
Safety Concerns Worth Knowing
For most healthy adults, Juice Plus appears safe based on available data. But there are specific situations where caution is warranted. Memorial Sloan Kettering Cancer Center advises against taking Juice Plus if you are undergoing chemotherapy or radiation therapy. The antioxidant properties of the supplement could theoretically interfere with treatments that work by generating free radicals to destroy cancer cells. Taking antioxidant supplements during these therapies may reduce their effectiveness.
There is also a documented case of liver problems linked to Juice Plus use. A 51-year-old woman with endometrial cancer developed elevated liver enzymes and experienced interference with her medical treatments while taking the product. After she stopped using it, her liver function returned to normal over four weeks. This is a single case report, not a widespread pattern, but it underscores the importance of disclosing all supplements to your healthcare team, especially during cancer treatment.
Quality and Certification
Juice Plus does carry third-party certification from NSF International, an independent organization that tests supplements for purity, label accuracy, and contamination. As of 2026, 29 Juice Plus products are certified under NSF’s Functional Foods guideline, covering the Berry, Fruit, and Vegetable blends in both capsule and chewable forms, along with their Complete shake powders and Perform product line. This certification means the products have been verified to contain what the label says and are free of harmful contaminants, which puts Juice Plus ahead of many supplements on the market that undergo no independent testing at all.
Is It Worth the Cost
Juice Plus typically runs between $70 and $90 per month depending on which blends you order, making it one of the more expensive supplement options available. Whether that price makes sense depends on your situation. If you already eat several servings of fruits and vegetables daily, the added benefit of a concentrated powder is likely minimal. If your diet is genuinely lacking in produce and you’ve struggled to change that, Juice Plus delivers real plant compounds that your body can absorb.
The MLM distribution model also means a portion of what you pay goes toward distributor commissions at multiple levels, not just toward the product itself. Similar fruit and vegetable powder supplements from other companies, sold through conventional retail, often cost significantly less. The NSF certification and the body of published research give Juice Plus some credibility advantages over generic alternatives, but the core concept of dehydrated produce powder is not unique to this brand.