Bioma is a probiotic supplement that combines three categories of gut health ingredients: probiotic bacteria, a prebiotic fiber, and a postbiotic compound. Each capsule uses delayed-release technology designed to protect its contents from stomach acid so they reach the intestines intact. Here’s a closer look at what’s actually in the formula.
The Probiotic Strains
Bioma’s probiotic blend contains three strains of Bifidobacterium, a genus of bacteria that naturally lives in the human gut and is one of the most widely studied groups in probiotic research:
- Bifidobacterium breve, which is associated with digestive comfort and has been studied for its role in breaking down dietary fibers
- Bifidobacterium lactis, one of the most common strains in commercial probiotics, linked to immune function and regularity
- Bifidobacterium longum, a strain that colonizes the gut early in life and has been studied for reducing occasional bloating and supporting the gut lining
The product label lists these three strains as a proprietary blend weighing 29 mg. Bioma’s marketing materials claim the capsules deliver over 40 billion CFUs (colony-forming units, the standard measure of live bacteria in a probiotic). However, the label does not break down how many CFUs come from each individual strain, which makes it difficult to compare directly against clinical studies that tested specific strains at specific doses.
The Prebiotic: Xylooligosaccharides (XOS)
Prebiotics are fibers that feed beneficial gut bacteria, and Bioma uses xylooligosaccharides, commonly abbreviated as XOS. Think of XOS as food for the probiotics in the capsule and for the good bacteria already living in your gut. It’s a type of plant-derived fiber that your body can’t digest on its own, so it passes through to the lower intestine where bacteria ferment it.
XOS has some research behind it. A pilot study published in the journal British Journal of Nutrition tested 2 grams per day of XOS in both healthy adults and those with prediabetes over eight weeks and found it altered gut bacteria composition. Bioma does not publicly disclose exactly how much XOS each capsule contains, so it’s unclear whether the dose matches what’s been studied clinically.
The Postbiotic: Tributyrin
Bioma also includes tributyrin, which it categorizes as a postbiotic. Postbiotics are compounds produced as byproducts of bacterial fermentation. Tributyrin is a precursor to butyrate, a short-chain fatty acid that cells lining the colon use as their primary energy source. Butyrate plays a role in maintaining the gut barrier, the layer of cells that separates what’s inside your intestines from your bloodstream. A healthy gut barrier helps prevent unwanted substances from crossing into the body.
The logic behind including tributyrin is that it delivers butyrate more reliably than hoping your gut bacteria will produce enough on their own. Tributyrin survives the upper digestive tract better than butyrate supplements taken directly, which tend to break down before reaching the colon. The exact amount of tributyrin per Bioma capsule is not listed on publicly available labels.
The Delayed-Release Capsule
One of the practical challenges with any probiotic is getting live bacteria past stomach acid, which kills a significant percentage of organisms before they reach the intestines where they’re needed. Bioma uses DRcaps, a delayed-release capsule technology. These capsules are designed to resist dissolving in the acidic environment of the stomach and instead open in the more neutral environment of the small intestine. This is a well-established capsule format used across many supplement brands, not something unique to Bioma.
What’s Not in It
Bioma positions itself as a clean formula. Unlike many probiotic products that include Lactobacillus strains alongside Bifidobacterium, Bioma’s current formulation focuses exclusively on the three Bifidobacterium strains listed above. The product does not appear to contain common fillers like magnesium stearate or silicon dioxide based on available label information, though the company does not prominently publish a full inactive ingredient list. Specific allergen information (gluten, dairy, soy) is not clearly disclosed on publicly available product listings, so if you have food sensitivities, contacting the company directly or reading the physical label before use is the safest approach.
Pricing
Bioma Probiotics starts at $25.99 per bottle at its lowest advertised price, which reflects bulk or subscription pricing. The company offers a 15% discount when you bundle three products together. Bioma also sells several other supplements beyond its core probiotic, including a digestive repair formula, fiber gummies, and a GLP-1 booster, with prices ranging from about $18 to $36 per bottle depending on the product.