What Is Hematospermia? Causes, Diagnosis, and Treatment

Hematospermia, the presence of blood in the semen, often causes immediate alarm. This condition, also known as hemospermia, occurs when bleeding originates from any structure along the male reproductive tract, from the testes to the urethra. While seeing blood in the ejaculate can be concerning, the cause is generally benign and self-limiting, particularly in younger men. However, because hematospermia can occasionally signal a more serious underlying health issue, a medical evaluation is always warranted.

Understanding the Appearance of Hematospermia

The physical appearance of the blood in the semen can provide clues regarding the timing and location of the bleeding. Bright red blood suggests a recent bleed, likely originating from the prostate or urethra, which are closer to the exit point. Conversely, a rusty, brown, or dark black discoloration indicates older blood, having resided in the seminal vesicles or other upper reproductive structures.

The frequency of the bleeding is also important; a single, isolated episode often has less significance than persistent or recurrent occurrences. Hematospermia is frequently an isolated symptom, meaning it occurs without other associated discomfort. When it is accompanied by symptoms like painful urination, fever, or pain with ejaculation, it may point toward an underlying infection or inflammation.

Identifying the Underlying Causes

The source of bleeding can be anywhere in the reproductive tract, including the prostate, seminal vesicles, epididymis, or urethra. In many cases, especially in younger men, the specific cause remains unknown and is classified as idiopathic, resolving on its own. The most common identifiable causes involve inflammation or infection within the genitourinary system.

Inflammation of the prostate (prostatitis) or seminal vesicles (seminal vesiculitis) is a frequent finding, particularly in men under 40. These inflammatory conditions may be caused by common bacterial infections or sexually transmitted infections (STIs), such as chlamydia or gonorrhea. Recent trauma from medical procedures, specifically a prostate biopsy or a vasectomy, is another common, temporary cause, with blood often visible for several weeks following the procedure.

Less common causes include structural or vascular abnormalities. These can involve cysts or stones (calculi) within the seminal vesicles or ejaculatory ducts that cause obstruction and bleeding. Vascular issues, such as varices (swollen veins) in the prostate or urethra, may also lead to hematospermia.

Systemic disorders, such as uncontrolled high blood pressure (hypertension) or underlying bleeding disorders, can also manifest as blood in the semen. While it is a common fear, cancer—including prostate, testicular, or bladder cancer—is an extremely rare cause of hematospermia, especially in younger men. When malignancy is the cause, it is typically seen in men over the age of 40 or those with other associated symptoms.

The Medical Evaluation and Diagnostic Process

The initial medical evaluation begins with a detailed review of the patient’s history, focusing on the duration of the bleeding and any associated symptoms like pain or fever. A physical examination, including a digital rectal examination (DRE) to assess the prostate and a genital examination, is performed to check for tenderness, masses, or urethral discharge. Blood pressure is often checked as a screening measure for severe hypertension, which can be a systemic cause.

The approach to laboratory testing differs based on a patient’s age and clinical presentation. For men under 40 with a single, isolated episode, the workup may be limited to a urinalysis and testing for STIs. Urinalysis is a simple, low-cost test that checks for a urinary tract infection or blood in the urine (hematuria), which may require a separate evaluation.

For men aged 40 or older, or those with recurrent or persistent hematospermia, a more extensive evaluation is typically required. This routinely includes a Prostate-Specific Antigen (PSA) blood test, which helps screen for prostate cancer. Imaging studies are often necessary in these higher-risk groups or if the initial workup is inconclusive.

Transrectal ultrasound (TRUS) is generally the first-line imaging choice, providing clear visualization of the prostate and seminal vesicles to identify cysts, calculi, or masses. If TRUS is normal or symptoms persist, magnetic resonance imaging (MRI) may be used as a second-line option because it offers superior soft tissue contrast for detailed pelvic anatomy. The specific diagnostic tools are selected to confirm the source of bleeding and rule out serious pathology.

Treatment Strategies and Outlook

Treatment for hematospermia depends entirely on the specific underlying cause identified during diagnosis. If the bleeding is determined to be idiopathic (no underlying cause found), the recommended approach is usually reassurance and watchful waiting. These self-limited episodes generally resolve on their own within a few weeks to months without specific intervention.

When an infection or inflammation is identified, the condition is treated with a course of appropriate antibiotics or anti-inflammatory medications. If a bacterial infection is suspected, a broad-spectrum antibiotic may be prescribed, sometimes covering both common bacteria and STIs in younger men. If the cause is a structural problem, such as a large seminal vesicle cyst or calculus, a urologist may need to perform specialized procedures.

Endoscopic procedures, such as seminal vesiculoscopy, can be used to directly visualize the seminal tract, remove stones, or fenestrate (create an opening in) cysts to relieve obstruction and stop the bleeding. If an underlying systemic issue, like a bleeding disorder or severe hypertension, is identified, treatment focuses on managing that specific condition. The prognosis for hematospermia is excellent, as the vast majority of cases are benign or easily treatable once the cause is pinpointed.