What Is Hematospermia and What Causes It?

Hematospermia, the presence of blood in the semen, is a condition that frequently causes significant alarm for those who experience it. While this symptom is understandably frightening, it is important to understand that in the vast majority of cases, it is a benign and self-limiting event. This is particularly true for younger men, where the symptom often resolves spontaneously.

How Hematospermia Presents

The appearance of blood in the semen offers clues about the source and timing of the bleeding. Bright red blood typically indicates fresh bleeding from an area closer to the point of ejaculation, such as the prostate or urethra. A rusty, dark brown, or black color suggests older, aged blood, often associated with the seminal vesicles, which store ejaculate for a longer duration.

The condition may present as a single, isolated episode or as intermittent occurrences. It is generally not painful, but it can sometimes be accompanied by other symptoms, such as discomfort during urination or ejaculation, depending on the cause. Clinicians differentiate cases based on age: hematospermia in men under 40 is frequently idiopathic and resolves on its own. For men over 40, however, it warrants a more thorough investigation due to the possibility of a serious underlying condition.

Potential Underlying Causes

The reproductive tract includes the testes, epididymis, vas deferens, seminal vesicles, and prostate; a lesion anywhere along this path can introduce blood into the semen. The most frequent identifiable causes are inflammation or infection within these structures. Conditions like prostatitis or seminal vesiculitis are common culprits. Urethritis and epididymitis, sometimes linked to sexually transmitted infections, can also lead to bleeding as the inflamed tissues become fragile.

Structural issues can also be responsible for the presence of blood. Blockages, such as ejaculatory duct obstruction caused by calcifications or cysts, can lead to a buildup of pressure that causes small blood vessels to rupture. Vascular abnormalities, including hemangiomas or varices (dilated veins) in the prostatic urethra, may bleed spontaneously during ejaculation. These structural causes often result in persistent or recurrent hematospermia.

Trauma is a frequent and easily identifiable cause, particularly trauma resulting from medical procedures (iatrogenic trauma). For instance, a prostate biopsy commonly causes hematospermia that can last for several weeks. Other procedures like vasectomy or radiation therapy for prostate cancer can also irritate tissues and result in bleeding. Severe physical injury to the genital area can less commonly rupture blood vessels in the reproductive organs.

While rare, systemic conditions or serious diseases can manifest with blood in the semen. Uncontrolled severe hypertension, for example, can cause blood vessels in the seminal vesicles to burst. Malignancies of the genitourinary tract, such as prostate, bladder, or testicular cancer, are occasionally found, although hematospermia is seldom the sole presenting symptom of these diseases. A significant proportion of cases, particularly in younger individuals with a single episode, remain idiopathic.

Investigating the Source

The medical workup for hematospermia begins with a detailed history and physical examination to narrow down the potential source of bleeding. The physician will ask about the duration of the symptom, any associated pain, and recent medical procedures or trauma. A physical examination includes checking the blood pressure for signs of severe hypertension and a genital examination to look for lesions or masses.

A digital rectal examination (DRE) is performed to assess the size, texture, and tenderness of the prostate gland and to check for any irregularities. Laboratory tests are often ordered, starting with a urinalysis and urine culture to check for infection or the presence of blood in the urine, which suggests a urinary tract source. For men over 40, or those with other risk factors, a Prostate Specific Antigen (PSA) blood test may be conducted to evaluate the prostate further.

If the initial assessment is inconclusive, imaging studies may be utilized to visualize the internal structures of the reproductive tract. The most common imaging test is the transrectal ultrasound (TRUS), which uses a probe inserted into the rectum to create detailed pictures of the prostate and seminal vesicles. For persistent or recurrent bleeding, or when a mass is suspected, a magnetic resonance imaging (MRI) scan of the pelvis may be performed for a more comprehensive view of the soft tissues.

Managing the Condition

The management strategy for hematospermia is directly determined by the underlying cause identified during the investigative phase. When an infection is confirmed, appropriate antimicrobial therapy, such as a course of antibiotics, is typically prescribed to clear the bacterial source. If inflammation without a clear infection is the issue, anti-inflammatory medications may be used to reduce swelling and irritation of the involved glands or ducts.

If structural abnormalities like cysts or obstructions are found, treatment may involve minimally invasive procedures to drain or relieve the blockage. When the cause is attributed to recent trauma or a medical procedure, the primary approach is observation, as the bleeding is expected to resolve on its own as the tissues heal.

For instances where the cause remains idiopathic, management involves watchful waiting and reassurance. The prognosis is overwhelmingly favorable, with most single episodes resolving spontaneously within a few weeks to a few months. Follow-up is advised if the bleeding persists beyond one month, recurs frequently, or is accompanied by systemic “red flag” symptoms such as unexplained weight loss, fever, or difficulty urinating, which would prompt further investigation.