What Is Eyebright and Does It Actually Work?

Eyebright, a small, flowering plant, has been used for centuries in traditional herbal practice, primarily to address issues related to eye health. The herb, belonging to the genus Euphrasia, has a long history of use for soothing irritated eyes, hence its common name.

Botanical Identity and Traditional Applications

Eyebright, encompassing several species in the genus Euphrasia, is a delicate annual herb native to Europe, Asia, and North America. The plant is characterized by small, white or purplish flowers often marked with a distinctive yellow spot near the center. It has a unique ecological trait, as it is a hemiparasite, meaning it draws some of its water and nutrients by tapping into the roots of nearby grasses.

The herb’s use for eye ailments dates back to at least the Middle Ages, with its Greek name, Euphrasia, translating to “gladness” or “delight,” referring to the joy of restored vision. This traditional application was reinforced by the “doctrine of signatures,” the historical belief that a plant’s physical characteristics indicated its medicinal use, with the flower’s appearance suggesting an eye. Historically, the herb was prepared as an external wash or poultice to treat various eye issues, including styes, conjunctivitis (pink eye), and general irritation and redness.

Key Active Compounds

Among the most studied components are the iridoid glycosides, particularly aucubin, which is thought to possess anti-inflammatory properties. Aucubin may also offer protective effects against oxidative damage in certain tissues. Eyebright also contains a significant concentration of flavonoids, such as luteolin and quercetin, which are known for their antioxidant activity. These compounds may help inhibit immune cells that release histamine, potentially giving the herb a role in managing allergy-related irritation. Additionally, the herb is rich in tannins and phenolic acids, which contribute an astringent quality that can help reduce swelling and dry up excessive secretions, a useful effect for inflamed mucous membranes.

Current Scientific Assessment of Efficacy

Modern research into eyebright has provided some preliminary insights into its biological actions, though high-quality human clinical trials remain limited. Laboratory studies involving human corneal cells suggest that certain eyebright extracts can decrease the expression of pro-inflammatory cytokines. Further in vitro studies indicate that eyebright extracts may exhibit antimicrobial properties against bacteria implicated in eye infections, such as Staphylococcus aureus.

A limited human study on individuals with eye inflammation from various causes, including allergies and infections, used eye drops containing eyebright and rose extracts. This study reported that the majority of participants experienced complete relief or noticeable improvement in symptoms like redness, swelling, and burning. However, this trial lacked a control group, making it difficult to definitively attribute the improvements solely to the eyebright extract.

Forms of Use and Safety Considerations

Eyebright is available in several forms, including liquid extracts, standardized capsules, and herbal tea. The herb is also frequently found in commercially prepared eye drops. For systemic support, capsules and teas are taken orally, with typical dosages ranging from 400–470 mg two to three times daily for capsules, or one to two teaspoons of dried herb for tea.

When applying eyebright to the eye, safety is paramount, as the eye is particularly susceptible to contamination. Topical preparations must be guaranteed sterile; using non-sterile homemade teas or compresses can introduce bacteria and potentially cause a secondary eye infection.

Side effects are uncommon but can include mild issues like headache, nausea, or stomach upset when taken internally. Eyebright may also lower blood sugar, so individuals with diabetes or those scheduled for surgery should exercise caution and consult a healthcare professional before use.