What Is Dermatosis Papulosa Nigra (DPN)?

Dermatosis Papulosa Nigra (DPN) is a common, non-cancerous skin condition presenting as small, hyperpigmented growths, primarily on the face and neck. This benign dermatosis affects a large number of people, particularly those with darker skin tones. The lesions often become a cosmetic concern as they increase in size and number over time. Understanding DPN involves defining its characteristics, cause, and available professional removal methods.

Defining Dermatosis Papulosa Nigra (DPN)

Dermatosis Papulosa Nigra is characterized by the appearance of small, dark papules that are typically dome-shaped or slightly elevated from the surrounding skin surface. These lesions range in color from a light brown to a deeper black and generally measure between one and five millimeters in diameter. While they can initially resemble tiny freckles, they gradually become more raised, with some taking on a filiform or stalk-like appearance over time.

The lesions most often develop symmetrically across the face, particularly on the cheeks, temples, and around the eyes, but they commonly extend onto the neck and upper trunk. DPN is considered a distinct clinical variant of seborrheic keratosis, a common benign epidermal growth. Histologically, DPN shares features with seborrheic keratosis, showing an overgrowth of keratinocytes and increased melanin within the epidermis.

DPN papules are harmless, making their removal purely elective. Although usually asymptomatic, some individuals report mild irritation or itching if the growths frequently rub against clothing or jewelry. Once they appear, these lesions do not spontaneously resolve and tend to increase in both size and quantity as a person ages.

What Causes DPN?

The exact cause of Dermatosis Papulosa Nigra remains unknown, but a strong genetic predisposition is widely recognized. A high percentage of individuals with DPN report a family history, suggesting it is an inherited trait. This hereditary link is supported because DPN is considered a variant of seborrheic keratosis, which also has a familial tendency.

The condition predominantly affects individuals with highly pigmented skin, specifically those categorized under Fitzpatrick skin types IV, V, and VI. It is particularly common among people of African, Asian, and Hispanic descent, with up to one-third of African American adults in the United States being affected. The lesions typically begin to appear during adolescence, which is earlier than the onset of typical seborrheic keratoses.

While genetics are thought to be the primary cause, the development of DPN is also often observed in sun-exposed areas, such as the face and neck. This observation has led researchers to suggest that ultraviolet (UV) light exposure may act as a contributing or modifying factor in genetically predisposed individuals. DPN is not caused by poor hygiene or any form of infection.

Treatment and Removal Options

Treatment for Dermatosis Papulosa Nigra is sought for cosmetic reasons. The primary goal of any removal technique is to eliminate the papule with minimal risk of scarring or causing post-inflammatory hyperpigmentation (PIH). Since PIH is a common concern in individuals with darker skin tones, procedure selection must be precise and conservative to protect the surrounding highly pigmented skin.

Electrodessication is one of the most common and effective methods, utilizing a low-level electrical current delivered through a fine probe to gently desiccate, or dry out, the lesion. The procedure is usually quick and may be performed after the application of a topical anesthetic for comfort. Following treatment, a small crust forms that naturally flakes off within one to two weeks, revealing smoother skin underneath.

Ablative laser therapies, such as the Carbon Dioxide (CO2) laser or the KTP (Potassium Titanyl Phosphate) laser, are highly effective, particularly for smaller lesions. These lasers precisely target the lesion’s tissue with minimal thermal damage to the surrounding skin, offering a controlled method of removal. Light curettage, which involves gently scraping the lesion off the skin surface, is another modality.

Cryotherapy, which uses liquid nitrogen to freeze the growths, is generally not preferred for DPN removal in darker skin types. The intense cold carries a higher risk of damaging the melanocytes, the cells that produce pigment. This damage can result in noticeable and long-lasting hypopigmentation (lighter spots) or hyperpigmentation at the treatment site. Consulting a dermatologist with experience treating skin of color is highly recommended to ensure the safest and most appropriate technique is selected, minimizing the risk of adverse pigmentary changes.