What Is CICO Weight Loss and How Does It Work?

Calories In, Calories Out (CICO), is the fundamental principle that governs weight management based on the physics of energy transfer. The concept states that your body weight is a direct result of the balance between the energy you consume and the energy you expend over time. This model is not a specific diet but a framework for understanding how the body processes the energy found in food and acts as the core mechanism for any weight change.

The Underlying Principles of Energy Balance

The CICO principle rests upon the First Law of Thermodynamics, which dictates that energy cannot be created or destroyed, only transformed. In the human body, energy derived from food is either used immediately or stored for later use, primarily as body fat.

When “Calories In” perfectly matches “Calories Out,” the body is in caloric maintenance, and weight remains stable. If “Calories In” exceed “Calories Out,” the body is in a caloric surplus, and the excess energy is stored, leading to weight gain. Conversely, weight loss requires a caloric deficit, forcing the body to draw upon stored energy reserves, such as body fat, to make up the difference.

Calculating Your Total Calorie Expenditure

The “Calories Out” side of the equation is Total Daily Energy Expenditure (TDEE), representing the total calories your body burns daily. TDEE is composed of several factors, the largest of which is the Basal Metabolic Rate (BMR). BMR is the energy required to maintain basic life-sustaining functions, such as breathing and circulation, and typically accounts for 60 to 75% of TDEE.

Beyond BMR, TDEE includes the Thermic Effect of Food (TEF), which is the energy used to digest and metabolize nutrients, making up about 10% of total expenditure. The remaining portion is dedicated to activity, which is divided into the Thermic Effect of Activity (TEA), covering structured exercise, and Non-Exercise Activity Thermogenesis (NEAT), including all other movement like walking or fidgeting.

To estimate TDEE, you first calculate BMR using formulas that consider age, sex, height, and weight. That BMR figure is then multiplied by an activity factor corresponding to your average daily movement level. While online calculators provide a convenient estimate, the result is only a starting point, as individual metabolism and movement patterns introduce variability.

Implementing the Calorie Deficit

Once TDEE is estimated, implementing a calorie deficit requires intentionally reducing “Calories In” below that maintenance level. A common and sustainable strategy is aiming for a daily deficit of approximately 500 calories. This reduction is generally associated with losing about one pound (0.45 kg) per week, as one pound of fat tissue is roughly equivalent to 3,500 calories.

Achieving this target demands consistent and accurate tracking of all food and drink intake, often using logging apps or a food diary. Utilizing a digital food scale to measure portions significantly improves the accuracy of the “Calories In” calculation. This precision is important because people often underestimate the calories they consume.

The deficit can be created solely through dietary reduction, by increasing physical activity to boost TDEE, or by combining both approaches. For example, a person could reduce food intake by 300 calories and burn an additional 200 calories through exercise to reach the target deficit. The chosen method must be sustainable long-term to prevent plateaus or regaining lost weight.

Why CICO Is Not the Only Factor

While CICO is an undisputed law of physics, focusing solely on the calorie number can be an oversimplification of real-world health and weight loss. The nutritional quality of food plays a substantial role in satiety and overall well-being, even when calorie counts are identical. Foods high in protein and fiber, for instance, promote greater feelings of fullness, making adherence to a deficit easier.

The body’s hormonal response is also not accounted for in the simple CICO equation. Different macronutrients affect hunger and satiety hormones, such as ghrelin, uniquely, influencing the drive to eat. Furthermore, a prolonged calorie deficit can cause metabolic adaptation, leading to a decrease in TDEE and the loss of muscle mass.