What Is Capillary Blood & Why Is It Used in Tests?

Blood circulates throughout the body, delivering substances and removing waste. It exists in different forms within the circulatory system, each collected through varied methods for medical analysis. Capillary blood is often used in routine medical tests due to its accessibility and the information it provides about a person’s health.

Understanding Capillary Blood

Capillary blood is found within capillaries, the smallest blood vessels in the body. These microscopic vessels form a network connecting tiny arteries (arterioles) to small veins (venules). Their walls are thin, often just a single cell thick, which facilitates the exchange of substances.

This blood is a mixture of oxygen-rich arterial blood, deoxygenated venous blood, and interstitial fluid. The primary function of capillaries is to allow water, oxygen, carbon dioxide, nutrients, and waste products to pass between the blood and surrounding tissues. This exchange occurs across the thin capillary walls, ensuring cells receive necessary supplies and waste is removed. Capillary blood samples are collected from sites like fingertips, earlobes, or the heels of infants.

Distinguishing Capillary Blood

Blood samples are collected in three main ways: from veins, arteries, or capillaries, each method providing a different perspective on the body’s internal state. Venous blood, collected through a procedure called venipuncture, is drawn from a vein, usually in the arm. This method yields a larger volume and is the standard for most routine laboratory tests, such as complete blood counts and cholesterol panels, as it reflects the overall systemic circulation.

Arterial blood is drawn directly from an artery, a more complex and less common procedure. This type of sample is used for blood gas analysis, which measures oxygen and carbon dioxide levels, providing a snapshot of respiratory and metabolic function. Arterial blood is oxygen-rich, in contrast to deoxygenated venous blood. Capillary blood is collected in smaller volumes. Its composition can differ slightly from venous blood, with analytes like glucose often higher in capillary samples, while proteins, calcium, and chloride may be lower.

Why Capillary Samples Are Used

Capillary blood samples are used in medical diagnostics due to several advantages. The collection method is minimally invasive, causing less pain and discomfort than traditional venous blood draws. This makes it suitable for children, the elderly, or individuals with fragile veins, as it reduces the risk of complications.

A small volume of blood is required for testing, often just a few drops. This makes capillary sampling ideal for tests that do not need a large quantity of blood. Common applications include regular blood glucose monitoring for diabetes management. Capillary samples are also used for newborn screening tests, which detect metabolic disorders like phenylketonuria (PKU), and for point-of-care testing, enabling rapid diagnostic results outside a laboratory. The convenience and speed of capillary sampling contribute to its use in various diagnostic and monitoring scenarios.

Collecting Capillary Blood

Collecting a capillary blood sample is a straightforward process. The first step involves preparing the collection site, usually a fingertip in adults and older children, or the heel in infants. The area is cleaned with an antiseptic wipe, and the skin must air dry to prevent sample dilution.

A small, sterile lancet is used to create a shallow puncture on the side of the fingertip or heel. The first drop of blood is wiped away, as it may contain tissue fluid that could affect test results. Subsequent free-flowing drops are collected into a small tube, onto a test strip, or directly onto a specialized device.

Gentle pressure or a downward arm position can help encourage blood flow. After collection, pressure is applied to the puncture site, and a small bandage may be used. The procedure is quick, and individuals experience only a brief prick or stinging sensation.