What Is Buprofezin? Uses, Pests, and Safety Concerns

Buprofezin is an insecticide used in agriculture and horticulture to manage insect pest populations. It belongs to the thiadiazine chemical class and functions specifically as an insect growth regulator (IGR). This compound offers a distinct approach to pest control, focusing on disrupting the life cycle of target insects rather than directly eliminating adult forms.

How Buprofezin Functions

Buprofezin operates by interfering with the biological processes that allow insects to grow and develop. As an insect growth regulator, it does not act as a rapid knockdown agent on adult insects. Instead, its primary mechanism involves inhibiting the synthesis of chitin, a complex carbohydrate polymer that forms the rigid exoskeleton of insects. This exoskeleton provides structural support and protection, and insects must shed it periodically through a process called molting to increase in size.

The disruption of chitin production means that immature insects, such as nymphs and larvae, cannot properly form a new, functional exoskeleton beneath their old one. When these immature stages attempt to molt, their compromised new cuticles cannot withstand the process, leading to their death. This action prevents immature insects from reaching adulthood and reproducing, thus controlling pest populations.

Common Applications and Target Pests

It is effective against sucking insects, which feed on plant sap and can cause significant crop damage. These include whiteflies, mealybugs, and various species of leafhoppers. The insecticide is also used to control scale insects and aphids, which are common issues in many crops. Buprofezin finds application on a variety of crops such as vegetable crops, citrus fruit trees, and cotton. It is also frequently utilized in controlled environments like greenhouses for the protection of ornamental plants.

Health and Environmental Considerations

From a human health perspective, buprofezin is generally considered to have low acute toxicity through oral and dermal exposure. Regulatory agencies classify it as having a low risk for direct human exposure during its handling and application. Furthermore, it is not currently classified as a carcinogen. However, buprofezin presents specific environmental concerns, particularly regarding aquatic ecosystems.

It exhibits high toxicity to aquatic invertebrates. The compound also shows moderate toxicity to fish species. Conversely, it has demonstrated relatively low toxicity to birds and bees, which can be beneficial for preserving non-target wildlife. Despite this, its persistence in water systems means that careful management is required to prevent runoff into water bodies.

Regulatory Oversight and Use Guidelines

The use of buprofezin is subject to strict regulatory oversight in many countries to ensure its safe and effective application. In the United States, for instance, it is registered under the authority of the Environmental Protection Agency (EPA). Its application is restricted to licensed applicators who work in agricultural or commercial settings, preventing widespread use by untrained individuals. Regulatory guidelines mandate specific safety measures, such as wearing personal protective equipment (PPE) during application to minimize exposure. Additionally, pre-harvest intervals (PHIs) are established for food crops, specifying the minimum time that must pass between the last application and harvest to ensure residue levels are below accepted limits.

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