nStride injection is a new medical treatment for joint pain. This biological therapy addresses underlying joint issues, especially those related to inflammation and cartilage health. It offers a non-surgical option to manage discomfort and improve joint function.
Understanding nStride Injection
nStride is an autologous protein solution (APS) derived from a patient’s own blood. This solution contains concentrated levels of anti-inflammatory cytokines and anabolic growth factors. The process involves separating white blood cells and platelets from a blood sample and concentrating them into a small volume of plasma.
In joints affected by conditions like osteoarthritis, inflammatory proteins are often more prevalent. nStride APS introduces high concentrations of anti-inflammatory proteins to counteract this imbalance. These components inhibit harmful inflammatory proteins, reducing inflammation and potentially slowing cartilage degeneration. The anabolic growth factors in nStride also stimulate cartilage matrix synthesis, contributing to damaged cartilage tissue repair. Unlike platelet-rich plasma (PRP) injections, nStride specifically includes leukocytes and anti-inflammatory cytokines.
Conditions Treated with nStride
nStride injection is primarily used to manage symptoms of mild to moderate osteoarthritis. This degenerative joint condition is characterized by pain and a loss of function due to cartilage damage. The treatment is commonly applied to large joints such as the knee, hip, and shoulder.
It is considered for patients whose pain has not adequately responded to more conservative treatments, including physical therapy or corticosteroid injections. While nStride aims to reduce pain and potentially slow cartilage degradation, it is not recommended for severe osteoarthritis where cartilage is extensively worn away. For such advanced cases, it is not a substitute for total joint replacement surgery, though it may help delay the need for it.
The nStride Treatment Process
The nStride treatment begins with an initial consultation to assess suitability. Once appropriate, a healthcare professional will draw a blood sample from a vein in the patient’s arm. This blood is placed into a specialized processing system, often a centrifuge, which spins the blood to separate its components. This process concentrates anti-inflammatory proteins, white blood cells, and growth factors into the autologous protein solution.
The preparation of the nStride solution takes about 20 to 30 minutes. After preparation, the injection site is thoroughly cleaned. The nStride APS is then injected directly into the affected joint, frequently guided by ultrasound imaging to ensure precise placement. Patients are able to go home within an hour of the procedure.
What to Expect After nStride
Following an nStride injection, patients may experience some soreness, swelling, or bruising at the injection site. This discomfort subsides within 24 to 48 hours. Over-the-counter pain relievers, such as paracetamol, can manage post-injection pain. However, anti-inflammatory medications like ibuprofen should be avoided for one to two weeks before and after the injection, as they can interfere with the treatment’s effects.
While some patients notice pain reduction within one to two weeks, substantial relief occurs between 2 to 8 weeks after treatment, with significant improvement taking up to 12 weeks. The benefits of a single nStride injection can last, with clinical studies suggesting pain reduction and improved mobility lasting up to 24 to 36 months. Patients are advised to minimize physical activities for 14 days post-injection to enhance effectiveness. Consulting with a healthcare professional is important to determine if nStride is a suitable option and to discuss individualized expectations.