What Is Acute Cor Pulmonale? Causes, Symptoms & Treatment

Acute cor pulmonale is a sudden heart condition caused by issues within the respiratory system. It presents an acute challenge to the heart’s right side, and its rapid onset can quickly lead to a decline in cardiovascular performance.

Understanding Acute Cor Pulmonale

Acute cor pulmonale is the sudden failure of the heart’s right ventricle. This happens when the right side of the heart struggles to pump blood into the lungs due to increased resistance in the pulmonary arteries. The right ventricle, which pushes deoxygenated blood into the lungs, is not designed to withstand high pressure.

When faced with this elevated pressure, the right ventricle dilates, stretching in length instead of thickening its walls. This stretching impairs its ability to pump blood efficiently, causing blood to back up. The term “cor pulmonale” means “pulmonary heart,” indicating the heart problem originates in the lung system.

What Causes Acute Cor Pulmonale

The primary cause of acute cor pulmonale is a massive pulmonary embolism. This occurs when a large blood clot, typically from the legs, travels to the lungs and obstructs a major pulmonary artery. This obstruction increases the pressure the right ventricle must overcome to pump blood, leading to its failure.

Other acute conditions can also trigger acute cor pulmonale by increasing pulmonary artery pressure. These include severe acute respiratory distress syndrome (ARDS) and acute exacerbations of chronic lung diseases. In ARDS, inflammation and fluid buildup in the lungs can constrict blood vessels. Mechanical ventilation used in ARDS can also contribute to this strain on the right ventricle.

Identifying the Symptoms

Individuals with acute cor pulmonale often present with sudden symptoms reflecting the heart’s struggle. A common sign is abrupt shortness of breath (dyspnea). This difficulty breathing often accompanies chest pain or discomfort, which can be mistaken for other cardiac events.

Other indicators include lightheadedness, dizziness, a rapid heart rate (tachycardia), and fainting (syncope). Signs of fluid backing up due to right heart failure, such as bulging neck veins (jugular venous distension) and swelling in the legs or belly (peripheral edema), may also appear. These symptoms require immediate medical attention.

Diagnosis and Treatment Approaches

Diagnosing acute cor pulmonale involves clinical assessment and diagnostic tools. An electrocardiogram (ECG) can reveal right heart strain. An echocardiogram, an ultrasound of the heart, visualizes the enlarged right ventricle and assesses its function, often performed rapidly at the bedside. If a pulmonary embolism is suspected, a computed tomography pulmonary angiography (CTPA) confirms blood clots in the lung arteries.

Treatment focuses on emergency measures and addressing the underlying cause. Oxygen therapy improves blood oxygen levels. Medications like vasopressors may support blood pressure and heart function. For a massive pulmonary embolism, thrombolytic therapy, which dissolves blood clots, is often an intervention. In some cases, embolectomy, the surgical removal of the clot, may be necessary.

Prognosis and Follow-Up Care

The outlook for individuals with acute cor pulmonale depends on factors such as the condition’s severity, the underlying cause, and how quickly effective treatment is initiated. Rapid diagnosis and prompt intervention improve outcomes. Addressing the primary cause, like a massive pulmonary embolism, is important for recovery.

Managing pre-existing chronic conditions that contribute to pulmonary hypertension is important to prevent recurrence or complications. Long-term medical follow-up is required to monitor heart and lung function and adjust therapies. Ongoing care focuses on preventing future episodes and supporting recovery.