What Is a Throat Ulcer? Causes and Treatments

A throat ulcer is an open sore that develops in the lining of the throat. These lesions can cause significant discomfort, making it difficult to eat, drink, or even speak. Unlike a general sore throat, an ulcer represents a physical break in the tissue, indicating a more specific underlying issue.

Understanding Throat Ulcers

Throat ulcers are open sores that can develop in various parts of the throat, including the pharynx, larynx (voice box), or esophagus, which is the tube connecting the throat to the stomach. They often appear as small, round, or oval sores with a white or yellowish center and a distinct red border. The size and number of these ulcers can vary widely depending on their cause. These lesions represent a disruption of the mucous membrane, the protective lining of the throat.

Common Causes

Several factors can lead to the development of throat ulcers. Viral infections are common causes, including herpes simplex virus, coxsackievirus, and Epstein-Barr virus. Bacterial infections, such as strep throat, or less commonly, syphilis and gonorrhea, can also cause these sores. Fungal infections, particularly candidiasis (thrush), can also cause throat ulcers, especially in individuals with weakened immune systems.

Gastroesophageal reflux disease (GERD), where stomach acid flows back into the esophagus and throat, is another common cause due to the irritant effect of the acid on the delicate lining. Physical injuries, such as those from medical intubation during surgery, consuming extremely hot food or liquids, or accidentally swallowing sharp objects, can create ulcers. Certain medications, including non-steroidal anti-inflammatory drugs (NSAIDs), bisphosphonates, and chemotherapy drugs, are known to weaken the mucosal lining, increasing susceptibility to ulcer formation. Underlying medical conditions like Behçet’s disease, Crohn’s disease, or specific cancers affecting the throat can also cause ulcers.

Recognizing Symptoms

Throat ulcers present with a range of symptoms that can vary based on the underlying cause and severity. A primary symptom is a severe sore throat, often described as a persistent, sharp pain. Individuals may experience significant pain or difficulty when swallowing, medically known as dysphagia. Changes in voice, such as hoarseness, can occur if the ulcers affect the vocal cords or surrounding areas.

A sensation of a lump or foreign object stuck in their throat, along with a persistent cough or frequent throat clearing, may also be reported. Other symptoms include fever, swollen lymph nodes in the neck, and bad breath.

Diagnosis and Treatment Approaches

Diagnosing a throat ulcer begins with a thorough medical history and a physical examination of the throat. A healthcare provider uses a small light and a tongue depressor to inspect the throat for sores. To identify the underlying cause, additional diagnostic tests may include a throat swab to test for bacterial or viral infections, or blood tests to check for systemic conditions. In some cases, an endoscopy, specifically a laryngoscopy or esophagoscopy, may be necessary to view the ulcers more closely or to obtain a tissue biopsy.

Treatment for throat ulcers depends on their cause. If an infection is present, antiviral, antibacterial, or antifungal medications are prescribed to target the specific pathogen. For ulcers caused by GERD, medications such as proton pump inhibitors (PPIs) or H2 blockers are used to reduce stomach acid production.

Pain relief is managed with over-the-counter medications like acetaminophen or ibuprofen, and sometimes medicated rinses or lozenges are recommended to numb the throat. Dietary modifications, such as consuming soft foods and avoiding acidic or spicy items, are advised to minimize irritation and promote healing. Maintaining adequate hydration is also important for recovery. For severe, persistent, or more serious underlying conditions, specialized medical treatments or ongoing monitoring may be required.

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