What Is a Skin Test and How Does It Work?

Skin tests are diagnostic tools that involve introducing a specific substance into the skin to observe a reaction. They are generally considered non-invasive procedures. These tests help healthcare providers identify conditions by observing how the immune system responds.

Why Skin Tests Are Performed

Healthcare providers often recommend skin tests to determine specific sensitivities or conditions. They primarily detect allergies, such as reactions to pollen, certain foods, medications, or insect venom. Skin tests also assist in diagnosing certain infections, like tuberculosis, by assessing the body’s immune response to specific antigens.

Different Kinds of Skin Tests

Several common types of skin tests are employed for diagnostic purposes. The Allergy Skin Prick Test, also known as a scratch test, is used to identify immediate allergic reactions. This test involves placing small amounts of potential allergens on the skin’s surface. The Allergy Patch Test helps detect delayed allergic reactions, often to chemicals or metals. Patches containing suspected allergens are applied to the skin, typically on the back.

The Tuberculosis (TB) Skin Test, or Mantoux test, screens for Mycobacterium tuberculosis infection. This test measures a delayed-type hypersensitivity reaction to a specific mycobacterial antigen. While less common than allergy tests, fungal skin tests can be used to diagnose certain fungal infections by observing a reaction to fungal antigens.

How Skin Tests Are Done

Administering a skin test begins with preparing the skin, often by cleaning the area, usually on the forearm or upper back. Patients may be advised to avoid certain medications, like antihistamines, as these can interfere with results. Small amounts of test substances are then applied to the skin. This can involve a tiny prick, adhesive patches, or a small injection.

After the substance is applied, a waiting period is necessary for the body to react. For prick tests, results are usually read within 15 to 20 minutes, while patch tests require wearing the patches for 48 to 96 hours. A healthcare professional then inspects the reaction site, measuring any resulting redness or swelling to determine the body’s response.

Interpreting Skin Test Results

Interpreting skin test results involves distinguishing between positive and negative reactions. A positive reaction typically manifests as a raised, red bump, often called a wheal, surrounded by redness. This indicates sensitivity or an immune response to the tested substance. Conversely, a negative reaction shows no visible change or only a minimal reaction, suggesting no sensitivity.

Several factors can influence the accuracy of skin test results, including certain medications, the patient’s age, and their overall immune status. These factors can sometimes lead to false positive or false negative results. Therefore, results must be interpreted by a healthcare professional who considers the individual’s medical history and symptoms. Further testing, a diagnosis, or a treatment plan may follow.