What Is a Pharyngeal Pouch? Causes, Symptoms & Treatment

A pharyngeal pouch is a rare medical condition characterized by a sac-like protrusion that forms in the throat area. This outpouching occurs due to a weakness in the muscular wall of the pharynx, allowing its lining to bulge outwards.

What Exactly Is a Pharyngeal Pouch?

A pharyngeal pouch is also known as Zenker’s diverticulum. It involves a sac forming in the posterior wall of the hypopharynx, the lower part of the throat just above the esophagus. This typically arises in Killian’s triangle, a naturally weaker point in the muscular wall at the junction of the pharynx and esophagus.

The pouch forms when the throat’s inner lining, the mucosa, pushes through this weakened muscular layer. As food passes, it exerts pressure on this weak spot. Over time, this pressure expands the lining outwards, forming a sac that collects food particles and saliva, which can lead to various complications.

What Causes a Pharyngeal Pouch?

A pharyngeal pouch develops from increased pressure within the lower pharynx combined with muscle weakness. During swallowing, the cricopharyngeal muscle, which forms a ring at the top of the esophagus, normally relaxes. If this muscle does not relax completely or contracts prematurely, it creates a high-pressure zone.

This elevated pressure then forces the pharyngeal lining outwards through Killian’s triangle, where the muscle wall is naturally less robust. The condition commonly affects older adults, which suggests an age-related component to muscle weakness and reduced coordination in swallowing. Gastroesophageal reflux disease might also contribute to cricopharyngeal muscle irritation and dysfunction.

How to Recognize the Symptoms

Individuals with a pharyngeal pouch often experience symptoms related to food and liquid trapping in the sac. Difficulty swallowing (dysphagia) is common, particularly with solid foods. This occurs as the pouch grows and obstructs food passage into the esophagus.

Regurgitation of undigested food is another characteristic symptom, which can happen hours after eating. Trapped food can also lead to halitosis (bad breath) due to its decomposition. Some people might notice gurgling sounds in their neck during or after swallowing, indicating air and fluid moving within the diverticulum.

A chronic cough or recurrent aspiration pneumonia can develop if contents from the pouch spill into the airways. This risk increases during sleep or when lying down, as the pouch can empty its contents into the trachea. Unexplained weight loss may also occur, as the discomfort and difficulty eating can lead to reduced food intake.

Diagnosing and Treating a Pharyngeal Pouch

Diagnosing a pharyngeal pouch begins with a review of symptoms and a physical examination. The most common and effective method for confirming a pouch is a barium swallow study, also known as an esophagram. During this X-ray procedure, the patient swallows a liquid containing barium, which coats the throat and esophagus, making the pouch visible.

Endoscopy, involving a flexible tube with a camera, can also identify a pouch. This procedure requires caution due to a slight risk of perforating the pouch wall if not performed carefully. Once diagnosed, treatment is generally recommended to alleviate symptoms and prevent potential complications like aspiration or malnutrition.

Treatment primarily involves surgical intervention to address the pouch and underlying muscle dysfunction. A common surgical approach is diverticulectomy, where the sac is surgically removed. This procedure is often combined with a cricopharyngeal myotomy, which involves cutting the cricopharyngeal muscle to relieve pressure. Less invasive endoscopic approaches are also available, where instruments are passed through the mouth to either divide the wall between the pouch and the esophagus or staple the pouch. The goal of any treatment is to improve swallowing function and prevent food from being trapped.