What Is a Blood Clot in the Brain? Causes and Symptoms

A blood clot in the brain is a serious medical event. Understanding its causes, signs, diagnosis, treatment, and prevention is crucial for timely intervention.

What a Brain Blood Clot Is

A blood clot in the brain, medically termed an ischemic stroke, happens when blood flow to a part of the brain becomes blocked. This blockage prevents brain cells from receiving the oxygen and nutrients they need, leading to cell damage and potential death within minutes. Ischemic strokes are the most common type of stroke, accounting for about 87% of all cases.

These clots can arise in two primary ways. A thrombotic stroke occurs when a blood clot, called a thrombus, forms directly within an artery in the brain, often in vessels already narrowed by fatty deposits. Conversely, an embolic stroke develops when a clot, known as an embolus, forms elsewhere in the body—frequently in the heart or large arteries—and then travels through the bloodstream until it lodges in a brain artery.

Understanding the Causes

Several factors can increase the likelihood of blood clots forming in the brain. A common contributing condition is atherosclerosis, characterized by the buildup of fatty deposits, or plaque, within the arteries. This process narrows blood vessels, making them more susceptible to clot formation.

High blood pressure, also known as hypertension, contributes to this risk by damaging artery walls over time. This damage can make blood vessels stiffer and narrower, creating an environment where clots can easily form. Another risk factor is atrial fibrillation (AFib), an irregular heartbeat where blood can pool in the heart, leading to the formation of clots that may then travel to the brain.

Other health conditions and lifestyle choices also play a role. Diabetes can damage blood vessels, increasing the risk of clot formation, while smoking directly harms blood vessels and promotes clotting. Obesity is linked to several risk factors for blood clots, including high blood pressure and diabetes.

Spotting the Signs

Recognizing the signs of a brain blood clot is important, as symptoms often appear suddenly. A widely used acronym to remember these signs is FAST: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services.

Facial drooping may be noticeable when a person tries to smile, with one side of the face appearing uneven. Arm weakness might present as one arm drifting downward when both are raised. Speech difficulty can include slurred speech, trouble finding words, or difficulty understanding what others are saying. If any of these signs are observed, it is important to call for immediate medical help.

Other symptoms that may indicate a brain blood clot include a sudden, severe headache without a known cause, changes in vision such as blurriness or loss of sight in one or both eyes, and sudden dizziness or loss of balance. Confusion or trouble understanding simple statements can also be a sign.

How Brain Clots Are Diagnosed and Treated

When symptoms of a brain blood clot appear, medical evaluation begins swiftly with a physical examination and a neurological assessment to check for signs of impaired brain function. Imaging scans are then important for confirming the presence, location, and type of stroke. A computed tomography (CT) scan is often one of the first tests performed, providing images of the brain to help determine if the stroke is ischemic (caused by a clot) or hemorrhagic (caused by bleeding). Sometimes, a CT angiogram, which involves injecting a dye, is used to visualize blood vessels in more detail. Magnetic resonance imaging (MRI) can offer a more detailed view of brain tissue, identifying areas damaged by an ischemic stroke.

Immediate treatment focuses on restoring blood flow to the affected brain area. For ischemic strokes, clot-dissolving medications called thrombolytics, such as tissue plasminogen activator (tPA), can be administered intravenously. This medication works by breaking down the blood clot, but it must be given within a specific time window, typically within 3 to 4.5 hours of symptom onset for effectiveness.

In some cases, a procedure called mechanical thrombectomy may be performed. This involves inserting a catheter into a blood vessel to physically remove the clot from the brain. This procedure can be effective for certain patients, often within a time window of up to 24 hours from symptom onset, depending on specific criteria.

Reducing Your Risk

Taking proactive steps can help reduce the chances of developing a blood clot in the brain. Lifestyle modifications are important for prevention. Adopting a healthy diet, engaging in regular physical activity, and maintaining a healthy body weight contribute to overall vascular health. Quitting smoking is also important, as tobacco damages blood vessels and promotes clot formation. Limiting alcohol consumption can further support circulatory health.

Managing existing health conditions is another important preventive measure. This includes consistently controlling high blood pressure through medication and lifestyle changes, as hypertension strains blood vessels. Keeping cholesterol levels and diabetes under control is also important, as these conditions can contribute to arterial damage. For individuals with atrial fibrillation, adhering to prescribed medications helps prevent the formation of clots that could travel to the brain.