2-Octyl cyanoacrylate is a specialized medical adhesive, often referred to as “surgical glue,” used by healthcare providers to close certain types of wounds. This liquid substance offers a less invasive alternative to traditional stitches or staples for joining skin edges.
What is 2-Octyl Cyanoacrylate?
2-Octyl cyanoacrylate is a synthetic liquid monomer. When this clear liquid contacts moisture, it rapidly undergoes polymerization, transforming into a solid, flexible film. This medical-grade adhesive is formulated to be less toxic and more flexible than common household super glues, which typically use ethyl cyanoacrylate. The resulting polymer creates a strong, pliable, waterproof barrier over the wound.
How It Works
The adhesive functions when liquid 2-octyl cyanoacrylate contacts anions in the skin’s natural moisture or blood. This triggers a rapid exothermic polymerization reaction, generating heat as it hardens. The newly formed polymer binds to the superficial skin epithelium, holding wound edges together. This protective film creates a watertight seal, preventing bacteria from entering the wound while allowing tissue to heal. As skin regenerates, the adhesive layer sloughs off, typically within 5 to 10 days, eliminating the need for removal.
Key Medical Applications
2-Octyl cyanoacrylate is used for closing easily approximated skin edges. It is applied to simple lacerations, especially in emergency departments, and to seal surgical incisions, including small punctures from minimally invasive procedures. Its application is favored for wounds where cosmetic outcomes are a concern, such as facial wounds, and in pediatric patients due to its pain-free application. This adhesive is suitable for wounds under low tension and with well-cleaned edges.
Benefits Over Traditional Methods
2-octyl cyanoacrylate offers several advantages over traditional wound closure methods like sutures or staples. Patients experience less discomfort during application due to no needle sticks, and the process is faster, reducing procedure time. The adhesive naturally sheds as skin heals, eliminating the need for follow-up visits for removal. This method can also lead to better cosmetic results, with less scarring compared to sutures. Additionally, the adhesive forms a microbial barrier, helping reduce infection risk by preventing bacteria from entering the wound.
Important Safety Information
2-octyl cyanoacrylate is not appropriate for all wound types and should only be applied by trained medical professionals. It is not recommended for deep wounds, puncture wounds, or wounds in areas of high skin tension, such as joints. Minor side effects can occur, including a temporary sensation of warmth or slight burning during application, or mild redness or swelling around the wound site. Patients should avoid scrubbing or picking at the adhesive as it heals, and limit prolonged water exposure to prevent premature erosion. Applying topical antibiotics or other medications directly over the adhesive is not advised, as this can compromise its integrity.