What Does Liver Cancer Look Like on an Ultrasound?

Early detection of liver cancer is important for effective treatment. Ultrasound, a common first-line imaging tool, helps visualize the liver’s structure and can reveal suspicious findings that might indicate cancer.

Understanding Liver Ultrasound

An ultrasound uses high-frequency sound waves to create real-time images of internal organs, including the liver. A technician applies a gel to the skin and moves a wand, called a transducer, over the abdomen. The transducer sends sound waves into the body, which bounce off tissues and return to the transducer. These reflected sound waves are then converted into detailed pictures on a computer screen.

Ultrasound is a non-invasive procedure that does not use ionizing radiation, making it a safe choice for many patients. Its accessibility and real-time visualization make it a common initial imaging method for evaluating liver health. It can help assess the liver’s size, texture, and the presence of masses or abnormalities.

Recognizing Liver Cancer’s Appearance

Liver cancer can manifest in various ways on an ultrasound, and radiologists look for specific visual characteristics. Tumors may appear as masses that are darker (hypoechoic) or brighter (hyperechoic) than surrounding liver tissue. Some lesions might exhibit mixed echogenicity, with varied light and dark areas. The edges of a cancerous mass can often appear irregular or poorly defined.

Increased blood flow within or around a suspicious mass is another indicator, which can be detected using Doppler ultrasound, a specialized technique that shows blood flow direction and speed. This increased vascularity, sometimes appearing as a “basket pattern” around the tumor, is a common feature of certain liver cancers. In some cases, liver cancer may not present as a distinct lump but rather as diffuse infiltration, where the cancer cells spread throughout the liver tissue. The number and size of lesions are also considered; a single large lesion or multiple smaller ones can be signs of malignancy.

Distinguishing Cancer from Other Liver Conditions

Interpreting liver ultrasounds is complex because many benign conditions can have appearances similar to cancerous lesions. For example, simple liver cysts typically appear as well-defined, anechoic (fluid-filled, appearing black) structures with thin walls. Hemangiomas, which are benign blood vessel tumors, often appear as homogeneous, hyperechoic (bright) masses with well-defined margins, though their appearance can vary.

Fatty liver disease, also known as hepatic steatosis, can make the liver appear diffusely brighter or more echogenic than normal. This increased brightness can sometimes obscure other findings or alter the typical appearance of lesions. Benign nodules, such as focal nodular hyperplasia, can also be present and may require further imaging for definitive characterization. Radiologists use their expertise to differentiate between benign and malignant conditions.

What Happens After an Abnormal Ultrasound

If a liver ultrasound reveals a suspicious finding, further diagnostic steps are typically necessary to determine its nature. The physician will order additional imaging tests, such as a computed tomography (CT) scan or magnetic resonance imaging (MRI), which provide more detailed views of the liver and better characterize the lesion. These advanced modalities often involve contrast agents to highlight abnormal tissues, improving diagnostic accuracy.

In some cases, a liver biopsy may be performed to obtain a tissue sample for microscopic examination, which is often the definitive method for diagnosing cancer. A multidisciplinary team of specialists, including radiologists, hepatologists, oncologists, and surgeons, collaborates to review the findings and develop a comprehensive treatment plan tailored to the individual patient.