What Does “Lith” Mean in Medical Terms?

The word “lith” in medical terminology originates from the ancient Greek word lithos, meaning “stone” or “rock.” This root is used as a prefix or a suffix to describe a hardened mass, formally known as a calculus (Latin for “little stone”), that forms within the body’s organs or ducts. These calcified masses, often composed of mineral salts, define several common medical conditions.

Understanding “Lith” in Medical Conditions

Medical terminology for conditions involving stone formation uses the root “lith” combined with the suffix -iasis (meaning a process or morbid condition). This results in the term lithiasis, which describes the formation of a calculus inside an organ. The specific location of the hardened mass determines the full name of the condition.

One of the most widely known examples is Nephrolithiasis, where nephros refers to the kidney, indicating the formation of kidney stones. A broader term is Urolithiasis, which refers to the presence of stones anywhere within the urinary tract, including the kidneys, ureters, bladder, and urethra. These urinary stones are typically composed of crystallized mineral salts found in concentrated urine.

When stones form within the gallbladder, the condition is termed Cholelithiasis, combining chole (bile) with “lithiasis.” Gallstones are typically formed from solidified cholesterol or bilirubin, and they can obstruct the flow of bile, leading to significant pain. Even the salivary glands can be affected by stone formation, a condition known as Sialolithiasis, where sialon means saliva. These salivary stones, or sialoliths, can cause painful swelling, particularly when the gland is stimulated to produce saliva.

Medical Procedures Involving “Lith”

Medical interventions to address these conditions often incorporate the “lith” root to describe the action of removing or destroying the stone. The most common action-based term is Lithotripsy, which literally means “stone crushing,” combining litho with -tripsy (to crush or break). This procedure utilizes focused energy to break up the hard calculus into smaller fragments that can be passed naturally.

The non-invasive method is Extracorporeal Shock Wave Lithotripsy (ESWL), which generates high-energy shock waves outside the body and directs them toward the stone. Alternatively, laser lithotripsy is an endoscopic technique where a thin scope is inserted to deliver a laser fiber directly to the stone, fragmenting it with localized energy.

For stones too large or difficult for crushing techniques, a surgical procedure known as Lithotomy may be performed. Lithotomy combines the root with -tomy (to cut or incise), meaning the surgical incision and removal of a stone. This procedure is more invasive than lithotripsy but is necessary when the calculus is too large or too impacted to be broken up.

Specific Stone Compositions and Formation

The chemical makeup of calculi varies significantly depending on their location and the underlying metabolic environment. The most prevalent type of kidney stone is the calcium stone, accounting for the majority of cases, typically composed of calcium oxalate or, less commonly, calcium phosphate. Formation results from a high concentration of these substances in the urine, often due to metabolic disorders or excessive calcium absorption.

Another common type is the uric acid stone, which forms when the urine becomes consistently too acidic, causing uric acid to crystallize. This type is often seen in individuals with gout or those who consume a high-protein diet that leads to increased uric acid production.

A third category is Struvite stones, also called infection stones, which are composed of magnesium ammonium phosphate. These stones almost always form following a urinary tract infection with specific bacteria that produce an enzyme called urease, which makes the urine highly alkaline.

Gallstones, in contrast to most kidney stones, are frequently classified as cholesterol stones, which are hardened masses primarily composed of cholesterol monohydrate. These form when bile contains too much cholesterol, not enough bile salts, or when the gallbladder does not empty properly.