What Do NPs Do? Roles, Specialties, and Pay

Nurse practitioners (NPs) examine patients, diagnose illnesses, prescribe medications, and manage ongoing health conditions. Their day-to-day work closely mirrors what a primary care physician does, and in many states, they practice independently without physician oversight. There are over 320,000 NPs working across the U.S., a number projected to grow 40% by 2034.

Core Clinical Responsibilities

NPs handle the full spectrum of a patient visit. They take health histories, perform physical exams, order and interpret lab work and X-rays, diagnose acute and chronic conditions, prescribe medications, and refer patients to specialists when needed. If you see an NP for a sore throat, a diabetes check, or a routine physical, the experience looks much the same as seeing a physician.

Beyond diagnosis and treatment, NPs spend a significant portion of their time on health education and counseling. They help patients manage chronic conditions like high blood pressure or diabetes, coach lifestyle changes, and coordinate care across a team that may include physicians, nurses, and social workers. Research on NP-led chronic disease management has shown meaningful improvements: one study found that patients in NP-led programs saw blood sugar levels, blood pressure, and BMI all drop significantly over a 12-week period.

How NP Care Compares to Physician Care

A systematic review published in Medical Care Research and Review found that patients treated by NPs were 11% less likely to be hospitalized than those treated by physicians, and also less likely to be hospitalized for conditions that good outpatient care should prevent. NPs also prescribed fewer potentially inappropriate medications, with patients seeing a 38% to 52% lower chance of receiving a risky prescription depending on how many chronic conditions they had.

NP-led transitional care programs (where patients are closely followed after leaving the hospital) have also been linked to fewer emergency department visits and hospital readmissions. One program cut ED visits by about 58% and hospital stays by 35% in the six months after patients enrolled, compared to the six months before.

Specialties NPs Practice In

NPs don’t all do the same work. They train and certify in specific population-focused specialties:

  • Family (FNP): The most common specialty, making up nearly 70% of all NPs. FNPs provide primary care to patients of all ages, from newborns to older adults.
  • Adult-Gerontology (AGNP): Focused on adults and elderly patients, either in primary care or acute settings like ICUs and emergency departments.
  • Pediatric (PNP): Works with children and adolescents, in either routine primary care or acute and critical care settings.
  • Psychiatric-Mental Health (PMHNP): Diagnoses and treats mental health conditions, substance use disorders, and emotional disorders. In many states, PMHNPs prescribe psychiatric medications independently.
  • Neonatal (NNP): Cares for premature or critically ill infants up to two years of age.
  • Women’s Health (WHNP): Provides gynecologic care, reproductive health services, and treatment for reproductive system disorders.

Prescribing Authority

NPs can prescribe controlled substances in all 50 states, though the rules vary. Twenty-two states grant full practice authority, meaning NPs prescribe with the same freedom as physicians. Sixteen states require a collaborative agreement with a physician, and the remaining states require direct physician supervision or delegation for controlled substances.

A handful of states have specific carve-outs. Georgia, Oklahoma, South Carolina, and West Virginia do not allow NPs to prescribe Schedule II medications (the most tightly regulated category, which includes drugs like oxycodone and amphetamines). Arkansas and Missouri limit NPs to prescribing only hydrocodone combination products within that same category.

Where NPs Work

NPs practice in primary care clinics, hospitals, urgent care centers, specialty offices, retail health clinics, community health centers, and telehealth platforms. Some run their own independent practices in states with full practice authority. Others work embedded in hospital departments like cardiology, oncology, or emergency medicine. The setting often depends on their specialty: a neonatal NP works in a hospital NICU, while a family NP might run a rural clinic as the sole provider for an entire community.

Education and Training Required

Becoming an NP requires a master’s or doctoral degree in nursing. Before entering an NP program, candidates must already be licensed registered nurses, meaning they’ve completed a bachelor’s degree in nursing and passed the national licensing exam. NP programs then add advanced coursework in pharmacology, pathophysiology, and clinical assessment, along with a minimum of 500 hours of supervised direct patient care. After graduating, NPs must pass a national board certification exam in their chosen specialty.

Pay and Job Outlook

The median annual salary for nurse practitioners was $129,210 as of May 2024, according to the Bureau of Labor Statistics. The field is one of the fastest-growing in healthcare, with employment expected to increase 40% between 2024 and 2034, adding roughly 128,400 new positions. That growth is driven by an aging population, a shortage of primary care physicians, and expanding state laws that allow NPs to practice more independently.

One financial detail worth knowing if you’re a Medicare patient: Medicare reimburses NP services at 85% of the physician rate. This doesn’t affect your copay in most cases, but it’s one reason healthcare systems increasingly rely on NPs to deliver cost-effective primary care.