What Do Eye Doctors Use to Dilate Pupils?

Pupillary dilation, often referred to as a “dilated eye exam,” is a standard procedure eye doctors use to temporarily widen the pupil. This process involves administering special eye drops that cause the small, circular opening at the center of the iris to significantly increase in size. This temporary enlargement creates a larger viewing port into the inner structures of the eye, allowing the practitioner to perform a comprehensive assessment of the eye’s internal health that is impossible when the pupil is at its normal size.

Why Dilation is Necessary

The natural size of the undilated pupil severely restricts the view of the eye’s posterior segment, which includes the retina, macula, and the optic nerve head. Without dilation, the doctor is limited to viewing only a small central area of this tissue. The dilated pupil provides a much broader and clearer field of view, necessary to check for subtle signs of conditions like changes in blood vessels, retinal tears, or alterations to the optic nerve. Dilation is also used in children and young adults to temporarily paralyze the eye’s focusing muscle, a process called cycloplegia. This ensures the most accurate prescription measurement possible by eliminating the eye’s ability to “over-focus.”

The Specific Medications Used

The medications used to achieve dilation fall into two main pharmacological categories. These drops work by targeting different muscles within the iris.

Mydriatics

The first category is mydriatics, which includes agents like phenylephrine. Phenylephrine stimulates the radial iris dilator muscle to contract and pull the pupil open, causing pupillary widening (mydriasis). This type of drop has minimal effect on the eye’s ability to focus.

Cycloplegics

The second category is cycloplegics, which are anticholinergic agents like tropicamide and cyclopentolate. These drops work by blocking the action of a neurotransmitter called acetylcholine. This blockade paralyzes the pupillary sphincter muscle, which normally constricts the pupil, and also paralyzes the ciliary muscle, preventing the eye from actively focusing. Tropicamide is the most common agent for routine dilation due to its rapid onset, typically taking effect within 10 to 15 minutes. Cyclopentolate is a stronger cycloplegic with a longer duration, often preferred when a more complete paralysis of the focusing mechanism is needed, particularly for children.

What to Expect After Dilation

After the drops are administered, patients will experience two primary, temporary side effects. The first is photophobia, or increased sensitivity to light, because the wider pupil allows more light to enter the eye. The second effect is blurred near vision, a direct result of the temporary paralysis of the focusing muscle (cycloplegia). Since the eye cannot adjust its focus for close objects, reading or working on a phone immediately after the exam becomes difficult.

The duration of these effects varies depending on the specific drops used. Tropicamide generally causes effects that wear off within four to eight hours, while Cyclopentolate’s effects last longer, sometimes taking up to 12 to 24 hours for full recovery. Patients are usually provided with dark-tinted sunglasses to manage photophobia. Because of the loss of sharp near vision, patients are advised to avoid driving or operating machinery until their vision has fully returned to normal, and arranging transportation home is recommended.